Comparing two acid reducers for stomach bleeding
Treatments studied
This trial tests two medicines that lower stomach acid to help stop bleeding from the stomach or intestines. It aims to find which one works better for people with this type of bleeding.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had signs of bleeding from the stomach or intestines within the last 5 days, like throwing up blood or black, tarry stools.
- A doctor confirmed the bleeding is not from swollen veins in the esophagus or stomach.
- You are between 18 and 75 years old.
- You can swallow pills and are willing to join the study.
- You do not have severe organ problems, a history of stomach surgery, or cancer that could affect your health.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a heartburn medication (pantoprazole) helps patients with liver cirrhosis who have had a procedure to treat enlarged veins in the esophagus or stomach. It looks at how well the medicine works when given after this procedure to prevent complications.
This trial compares two types of acid-reducing medicines to see which is better at preventing re-bleeding in people who have had severe ulcer bleeding. If you qualify, you would receive either a new acid blocker or a double dose of a standard acid reducer.
This trial compares two acid-reducing medicines—Tegoprazan and Lansoprazole—to see which works better for stopping bleeding from a peptic ulcer. If you have a confirmed upper GI bleed from an ulcer, this study may help find the best treatment for you.
This trial tests whether a newer drug, tegoprazan, works as well as the standard drug lansoprazole for healing bleeding ulcers in the stomach or small intestine. You will get one of these drugs for 14 days and have a follow-up endoscopy to check healing.
This trial compares an IV “acid-suppressing” medicine (PPI infusion) with acid pills (oral PPIs) after doctors treat a bleeding peptic ulcer endoscopically. It may help prevent re-bleeding by keeping stomach acid low while the ulcer heals.
This trial compares a potassium-competitive acid blocker to a proton pump inhibitor to help prevent stomach or intestinal bleeding in people at high risk who take blood-thinning medicines. It may help reduce dangerous GI bleeding while you stay on heart/stroke medicines.
Hear when a new Non-variceal Upper Gastrointestinal Bleeding trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.