Comparing Two Medicines to Prevent Ulcers After Vein-Tying Treatment
Treatments studied
Part of Digestive system clinical trials.
This study tests two different acid-reducing medicines (rabeprazole and vonoprazan) to see which one better prevents painful ulcers that can develop after a procedure to tie off bleeding veins in the esophagus. If you have cirrhosis and bleeding veins, this trial may help protect your healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years of age or older
- Have cirrhosis (liver scarring) confirmed by a doctor
- Have enlarged bleeding veins in your esophagus confirmed by endoscopy (a camera exam)
- Not currently taking acid-reducing medicines (PPIs) or vonoprazan for other conditions
- Not taking blood thinners or antiplatelet medicines (like aspirin or clopidogrel)
- Not have been diagnosed with liver cancer (HCC)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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