Varenicline for cannabis use disorder
Treatments studied
Part of Mental health clinical trials.
This study tests whether varenicline (a medication used to help quit smoking) can help people reduce or stop cannabis use. You may be eligible if you are an adult with cannabis use disorder who uses cannabis frequently and do not have certain medical or psychiatric conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a diagnosis of cannabis use disorder.
- You have used cannabis at least 3 days per week in the past month.
- You can read and understand English.
- You agree to use birth control if you could become pregnant.
- You do not have severe kidney problems.
- You have no history of bipolar disorder, schizophrenia, or other psychotic disorders.
- You have not had suicidal thoughts or behaviors in the last 6 months.
- You have not used certain other psychiatric medications (like bupropion or nortriptyline) recently.
- You do not have a moderate or severe substance use disorder (other than nicotine).
- You have not had significant heart or blood vessel disease in the last 6 months.
- You have no allergy to varenicline.
- You have not participated in another investigational drug study within the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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