Varenicline for treating cannabis use disorder
Treatments studied
Part of Mental health clinical trials.
This study tests whether a medication called varenicline (often used to help people stop smoking) can help reduce cannabis use in people with cannabis use disorder. If you qualify, you'll receive the medication or a placebo and be followed to see how it affects your cannabis use.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have a diagnosis of cannabis use disorder (problematic cannabis use).
- You must use cannabis at least 3 days a week on average.
- You must be able to read and understand English.
- You must be willing to take the study medication and follow study procedures.
- If you can become pregnant, you must agree to use effective birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether a medication called varenicline (or a placebo) can help people who use both tobacco and cannabis to quit or cut back. It takes place in South Carolina and lasts 12 weeks.
This trial tests if varenicline, a stop-smoking medication, can help people ages 18 to 40 quit e-cigarettes while also using cannabis. It's designed for regular e-cigarette users who want to quit and who use cannabis at least 10 days per month.
This trial tests whether varenicline helps people with schizophrenia or schizoaffective disorder stop smoking. It also looks at related nervous-system side effects that can happen with some anti-psychotic medicines.
This Phase 2 study tests whether extended-release guanfacine can reduce cannabis use in adolescents and young adults. It may help by targeting brain pathways that can drive cravings or continued use.
This trial tests whether tirzepatide, a medicine used for type 2 diabetes and weight loss, can help people with severe cannabis use disorder cut down or quit. It may reduce cravings and other symptoms of withdrawal.
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