Understanding persistent face and mouth pain
Part of Ear, nose & throat, Pain clinical trials.
This study uses brain scans (MRI) to better understand persistent pain in the face or mouth (PIFP) compared to people without pain. If you join, you'll have an MRI and possibly some mild stimulation to help researchers learn more about the condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You either have persistent pain in your face or mouth (PIFP), or you are a healthy volunteer with no pain.
- You must be able to have an MRI scan safely.
- You do not have anxiety disorders (including claustrophobia) or other pain conditions.
- You do not have other primary headaches or medication-overuse headache.
- You have no skin problems, infection, or scarring at the stimulation sites.
- If you are a healthy volunteer, you and your first-degree relatives have no history of persistent pain or primary headache.
- You have no history of psychiatric illness or addiction.
- You are not pregnant or breastfeeding.
- You do not take regular medication; PIFP patients may use occasional painkillers (like NSAIDs) less than 8 days a month.
- You must not have used painkillers within 24 hours before the experiment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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