Comparing hormone treatments for uterine protection in women on estrogen therapy
Part of Women’s health & pregnancy clinical trials.
This study looks at how different progestogen treatments (like the Mirena IUD) are used to protect the uterus lining in women over 40 who take estrogen therapy. It will help understand which options work best for preventing endometrial problems, and you won't receive any experimental treatment – just sharing your health information.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 40 years old or older.
- You still have your uterus (you have not had a hysterectomy).
- You are currently taking estrogen therapy.
- You have not used hormonal birth control (like the pill, patch, ring, or hormonal IUD) in the past year.
- You have not had unusual vaginal bleeding or a diagnosis of uterine (endometrial) cancer in the past year.
- You have continuous health insurance coverage for at least 1 year before and after you started estrogen therapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a weight-management approach plus a progesterone-releasing IUD (LNG-IUS) and megestrol to treat endometrial atypical hyperplasia, a high-risk precancer of the uterine lining. It may help shrink or control the abnormal cells while supporting fertility or keeping the uterus.
This study looks at whether a hormone-releasing IUD (LNG-IUS) can treat early-stage endometrial cancer or very early abnormal cell growth while helping you keep the option for future pregnancy. It aims to see how well the treatment works and how it affects fertility-related outcomes.
This study is developing a tool to help women decide if using a hormone-releasing intrauterine device (IUD) is right for them to lower their risk of endometrial cancer. Researchers are interviewing women at different risk levels and healthcare providers to make the tool useful and easy to understand.
This study compares two ways to give progesterone to young people on estrogen replacement therapy to see how they affect the lining of the uterus. It will help find which approach may be safer and more effective for your health.
This study compares two types of hormone therapy for menopause symptoms: one is a pill taken by mouth (dydrogesterone), and the other is a vaginal gel or suppository (progesterone). The goal is to see which one works better and is safer, so you and your doctor can choose the best option.
This study compares two types of intrauterine devices (IUDs) – one that uses copper and one that uses a hormone called levonorgestrel – to see how they affect the natural bacteria and protective barrier in the vagina. It aims to find out if one type is better at helping young women stay healthy and prevent infections, including HIV.
Hear when a new Estrogen Therapy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.