Comparing two hormone therapies for menopause symptoms
Treatments studied
Part of Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study compares two types of hormone therapy for menopause symptoms: one is a pill taken by mouth (dydrogesterone), and the other is a vaginal gel or suppository (progesterone). The goal is to see which one works better and is safer, so you and your doctor can choose the best option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 45 and 60 years old.
- You have gone through menopause (no periods for at least 12 months).
- You have not had your uterus removed (you have an intact uterus).
- You are having menopause symptoms like hot flashes or night sweats that need treatment.
- You have not had breast or uterine cancer, unexplained vaginal bleeding, blood clots, severe liver disease, or uncontrolled high blood pressure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how menopausal hormone therapy affects the brain and heart during menopause. It aims to see if starting hormone therapy can help improve heart and brain health in women with bothersome hot flashes.
This study looks at how menopausal hormone therapy (medicines that replace hormones your body no longer makes) affects your breasts and blood vessels. If you join, you'll be followed for a year to see how the treatment works for your symptoms and how it impacts your health.
This Phase 3 study compares two types of progesterone—micronized progesterone versus norethisterone acetate—both used with estrogen to treat menopause symptoms that affect daily life. It aims to see which combination works better and is tolerated over time for women with an intact uterus.
This study compares two vaginal treatments—DHEA and estradiol—to help relieve common menopause symptoms like dryness, itching, or discomfort during sex. You'll use vaginal therapy (applied directly where symptoms occur) and help researchers understand which works better.
This study compares two ways of giving progesterone to postmenopausal women. It aims to see how the body absorbs each form, which may help guide future treatment options.
This study compares two ways to give progesterone to young people on estrogen replacement therapy to see how they affect the lining of the uterus. It will help find which approach may be safer and more effective for your health.
Hear when a new Menopausal Women trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.