Clin2
NCT07798674Likely a fitRecruiting

Natural history study for ataxias and spastic paraplegias

Hereditary Spastic ParaplegiaSpastic Ataxia

Part of Brain & nervous system, Genetic & congenital clinical trials.

This study tracks how ataxias and related movement disorders progress over time. By joining, you help researchers learn more about these conditions and prepare for future treatments.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
4,000 people
Ages
5 years and older
Study type
Observational

Who can take part

  • You are 5 years old or older.
  • You have a diagnosis of ataxia, spastic ataxia, hereditary spastic paraplegia (HSP), or a related condition, OR you carry a gene change that can cause one of these conditions, OR you are a family member or healthy volunteer.
  • Your doctor has ruled out other causes for your symptoms.
  • You are able to attend study visits and follow study procedures.
  • You are not currently in another interventional study that could affect this one.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT03981276Recruiting
Study aims to understand inherited walking stiffness disorders

This study looks at the causes and biology (“biomarkers”) of hereditary spastic paraplegias and related conditions. You may join as someone with the condition, a family member without symptoms, or a healthy person, to help researchers understand what’s happening in the nervous system.

Innsbruck
NCT03206190Recruiting
Study for early SPG4 symptoms in family members

This study looks at people in families with a known SPG4 gene change (a SPAST mutation) to understand early, subtle signs and the beginning of symptoms. It may help researchers find better ways to detect SPG4 earlier, before full walking problems start.

Tübingen
NCT04712812Recruiting
Study of childhood-onset hereditary spastic paraplegia

This study follows people with hereditary spastic paraplegia that started in childhood to better understand how the condition progresses over time. It may help doctors learn what to expect and how to plan care, using genetic information and family history.

Boston, Massachusetts
NCT06572046Recruiting
Registry for hereditary spastic paraplegia (HSP)

This registry collects information from people with hereditary spastic paraplegia or spastic ataxia to help plan future treatments. It aims to better understand the condition and connect patients with potential therapies.

Pisa
NCT06553976Recruiting
Research network for hereditary spastic paraplegia

This trial aims to build a research network and gather information from people with two genetic types of hereditary spastic paraplegia (SPG4 and SPG5A). It will help doctors better understand these conditions and improve care.

Miami, Florida
NCT02440763Recruiting
Study of inherited progressive balance and coordination changes

This is a natural history study that follows people with inherited forms of “ataxia” (problems with balance and coordination) over time. It may help researchers better understand how these conditions progress in daily life and can inform future treatments.

Innsbruck

Hear when a new Hereditary Spastic Paraplegia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.