Study of a new pill for moderate-to-severe eczema
Part of Genetic & congenital, Immune system & allergy, Skin clinical trials.
This trial tests an experimental medicine called QX-4533. The study has two parts: one tests the drug in healthy volunteers, and the other tests it in people with moderate-to-severe atopic dermatitis (a type of eczema) that hasn't responded well to standard creams. The goal is to see if the drug is safe and how well it works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old (atopic dermatitis part) or 18 to 55 years old (healthy volunteer part).
- For the eczema part: you have had moderate-to-severe atopic dermatitis for at least 1 year and standard prescription creams (topical corticosteroids or calcineurin inhibitors) haven't worked or you can't use them.
- You are willing to use a moisturizer (emollient) twice a day for at least a week before starting and throughout the study.
- You are generally healthy, with no ongoing infections or major medical conditions.
- If you are a woman of childbearing age, you must not be pregnant or breastfeeding and agree to use contraception; if you are a man with a partner of childbearing potential, you must agree to use contraception and not donate sperm.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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