Radiation before surgery for advanced rectal cancer
Part of Cancer, Digestive system clinical trials.
This trial compares giving radiation therapy before surgery versus going straight to surgery for people with advanced rectal cancer that has not spread to other parts of the body. It aims to see which approach may be better for controlling the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have rectal cancer that is locally advanced, meaning it has grown into nearby tissues but has not spread to distant organs.
- Your cancer is in the proximal (upper) part of the rectum.
- You have no cancer spread to distant parts of the body (no distant metastasis).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests giving radiation, chemotherapy, and immunotherapy before surgery for rectal cancer that has not spread far. The goal is to see if this combination shrinks the tumor more and improves outcomes before surgery.
This study tests a specific “before surgery” treatment (radiation plus chemotherapy), followed by more chemotherapy to improve outcomes in people with certain types of rectal cancer. You might be considered if your cancer is locally advanced but not spread to distant organs.
This study tests a sequence of chemotherapy and radiation before and after surgery for rectal cancer. It compares giving more chemo between the end of radiation and surgery (consolidation) versus giving some chemo before radiation starts (induction). The goal is to see which order works better.
This study follows real-world treatment of locally advanced rectal cancer (cancer that has grown into nearby tissues but hasn't spread to distant organs) in patients who receive chemotherapy and/or radiation before surgery. Researchers track how different treatment approaches work to help improve outcomes.
This trial tests a new way of giving radiation therapy before surgery for rectal cancer. It uses a higher dose to the tumor during standard radiation to see if it can improve outcomes.
This study compares two approaches for a small, early-stage rectal cancer (T1N0). Some people get chemoradiotherapy before the tumor is removed, while others go straight to surgery. The goal is to see if adding chemoradiotherapy lowers the chance of the cancer coming back.
Hear when a new Rectal Adenocarcinoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.