Chemo and radiation before and after surgery for rectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study tests a sequence of chemotherapy and radiation before and after surgery for rectal cancer. It compares giving more chemo between the end of radiation and surgery (consolidation) versus giving some chemo before radiation starts (induction). The goal is to see which order works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have rectal cancer that has been confirmed with a biopsy.
- Your cancer is locally advanced (it has grown into nearby tissue but has not spread to distant organs).
- You have not received any chemotherapy or radiation for this cancer yet.
- You are between 18 and 75 years old.
- Your tumor is microsatellite stable (MSS) or proficient mismatch repair (pMMR).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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