Radiation and chemo before surgery for early rectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study compares two approaches for a small, early-stage rectal cancer (T1N0). Some people get chemoradiotherapy before the tumor is removed, while others go straight to surgery. The goal is to see if adding chemoradiotherapy lowers the chance of the cancer coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your tumor is rectal adenocarcinoma confirmed by biopsy.
- The tumor is located within 10 cm of the anal verge (measured by rigid proctoscopy).
- Staging shows the tumor is T1N0 (no spread to lymph nodes or distant sites).
- The tumor is 4 cm or smaller as measured by MRI.
- Your general health is good (ASA III or lower).
- You have no distant metastases, as confirmed by CT and chest X-ray.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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