Chemoradiotherapy and surgery vs. surgery alone for early rectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial compares two ways to treat early-stage T1 rectal cancer. One group gets standard local surgery after chemotherapy and radiation, while the other gets surgery alone. The goal is to see if adding chemoradiotherapy helps reduce the chance of cancer coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your tumor must be stage T1 (early, hasn't spread into deeper layers) and N0 (no lymph node involvement) based on MRI and endoscopy.
- The tumor must be 4 centimeters or smaller and located within 10 cm of the anal opening.
- You must be healthy enough for surgery (ASA score III or less).
- No spread to other organs (like liver or lungs) on CT scans.
- Your biopsy must not show aggressive features like undifferentiated cells or cancer in blood/lymph vessels.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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