Clin2
NCT07809607Possibly a fitNot yet recruiting

Study of YF087 for advanced solid tumors with MSI-H or dMMR

Advanced Solid Tumor Cancer

Part of Cancer clinical trials.

This trial tests a new drug called YF087 in people with advanced solid tumors that have a specific genetic feature (MSI-H or dMMR). It may help if your cancer has grown despite previous treatment, including a PD-1/PD-L1 inhibitor.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
70 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have an advanced solid tumor that cannot be removed by surgery or has spread to other parts of the body.
  • Your tumor has a genetic marker called MSI-H or dMMR (your doctor can test for this).
  • Your cancer has progressed after your most recent treatment, and you have already tried a PD-1 or PD-L1 inhibitor (a type of immunotherapy).
  • You have at least one measurable tumor that can be seen on a CT or MRI scan.
  • You are physically active and able to take care of yourself (ECOG score of 0 or 1).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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