Clin2
NCT07815522Possibly a fitRecruiting

Abiraterone with dalpiciclib for salivary gland cancer

Salivary Gland Carcinoma

Part of Cancer, Mouth & dental clinical trials.

This trial tests a combination of two targeted drugs for advanced salivary gland cancer that has spread or cannot be removed with surgery. The drugs may block hormones and slow cancer growth, potentially helping people whose tumors have specific markers.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
36 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old
  • You have advanced or recurrent salivary gland cancer that cannot be surgically removed and shows a certain marker (AR-positive, HER2-negative)
  • Your tumor sample is available for testing
  • You are generally in good health (able to care for yourself, with normal organ function)
  • You have not had anti-androgen therapy or CDK4/6 inhibitors before
  • You are willing to use effective contraception if applicable

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06145308Recruiting· Phase 2
Precision treatment for salivary gland cancer

This trial tests a personalized treatment approach for recurrent or metastatic salivary gland cancer. It uses special tests on your tumor to find the best targeted therapy for your specific cancer type.

Beijing, Beijing Municipality
NCT07464366Recruiting· Phase 2
MRG003 with or without putrelimab for salivary gland cancer

This trial tests a new drug combination (MRG003 with or without putrelimab) for people with advanced salivary gland cancer that has EGFR protein. It aims to see if the treatment is safe and helps shrink tumors.

Shanghai, Shanghai Municipality
NCT05513365Recruiting· Phase 2
Dutasteride added to anti-androgen treatment for salivary cancer

This Phase 2 trial studies whether adding dutasteride to standard anti-androgen therapy can shrink or slow an advanced salivary gland cancer. It is for cancers that test “androgen receptor (AR) positive,” meaning they may respond to medicines that block male-hormone signals.

Nijmegen, Gelderland
NCT06500247Not yet recruiting· Phase 2
Combination therapy for advanced hormone-resistant prostate cancer

This trial tests a combination of two oral medications (darxiciclib and abiraterone) for men with advanced prostate cancer that has spread and no longer responds to standard hormone therapy. It may help if you have already tried one newer hormone therapy and are looking for another option.

Jinan, Shandong
NCT06348264Recruiting· Phase 2
Rezvilutamide with hormone therapy for high-risk salivary duct cancer

This trial tests a new drug, Rezvilutamide, combined with standard hormone therapy for people with a rare and aggressive type of salivary gland cancer that has a high risk of coming back. The treatment aims to reduce the chance of cancer returning after surgery.

Beijing, Beijing Municipality
NCT07579598Not yet recruiting· Phase 2
Targeted therapy and radiation for advanced salivary gland cancer

This trial tests a combination of a targeted antibody-drug and focused radiation for people with advanced or recurrent salivary gland cancer that has spread. It aims to see if this treatment can help control the disease when standard treatments have stopped working.

Hear when a new Salivary Gland Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.