Clin2
NCT07819838Possibly a fitNot yet recruiting

Daraxonrasib for children with RAS-mutant solid tumors

Recurrent Childhood Malignant Solid NeoplasmRecurrent Childhood NeuroblastomaRecurrent Childhood RhabdomyosarcomaRefractory Childhood Malignant Solid NeoplasmRefractory Childhood NeuroblastomaRefractory Childhood Rhabdomyosarcoma

Treatments studied

Part of Cancer clinical trials.

This study tests a new drug (daraxonrasib) for children with solid tumors that have a RAS mutation and have not responded to standard treatments. The drug targets the mutated RAS protein to slow or stop cancer growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
77 people
Ages
1 year to 17 years
Study type
Interventional

Who can take part

  • Your child must be between 1 and 17 years old.
  • The cancer must be a solid tumor (not in the brain) that has come back or not improved after treatment.
  • A test must show a RAS mutation (a specific change in the KRAS, NRAS, or HRAS genes).
  • Your child must have recovered from side effects of previous treatments like chemotherapy or radiation.
  • Your child must be able to swallow tablets whole.
  • Your child must not have had a transplant or certain treatments within specific time frames before starting.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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