Weight loss study for people with excess weight
Treatments studied
Part of Hormones & metabolism clinical trials.
This study tests an investigational medicine for weight loss in people with excess weight. It aims to see how effective the medicine is and may help you lose weight and improve health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are male or female (sex at birth).
- If you have type 2 diabetes, your diabetes must have been diagnosed at least 6 months ago and your average blood sugar (HbA1c) must be between 7.0% and 10.0%.
- If you have type 2 diabetes, you must be on a stable treatment of lifestyle changes and/or up to 3 diabetes pills (like metformin, sulfonylureas, etc.).
- If you have knee osteoarthritis (OA) in one knee, you must have had pain in that knee for more than 90 days, and the pain must have been present on more than 15 days in the last month.
- You have not taken any GLP-1 or dual GLP-1/GIP receptor agonist medicines (like Ozempic, Wegovy, Mounjaro) before.
- If you do not have type 2 diabetes, your HbA1c must be below 6.5%.
- If you have type 2 diabetes, you must not have had a history of severe low blood sugar without warning, or recurrent severe lows in the past year.
- If you have type 2 diabetes, your kidney function must be moderate or better.
- If you have type 2 diabetes, you must not have active diabetic eye disease that has been treated recently.
- If you have knee OA, you must not have had a joint replacement or any prior surgery in that knee, and no injections or arthroscopy in that knee in the last 90 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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