Comparing two hormone therapy schedules for brain health in menopause
Part of Brain & nervous system, Women’s health & pregnancy clinical trials.
This study compares two ways of taking estrogen during menopause to see which one better supports memory and thinking. You would receive either a steady dose or a pulse dose of estrogen, along with a progestin, and researchers will track your brain health over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 38 and 60 years old.
- You went through menopause (your last period) 12 to 48 months ago.
- You have not used hormone therapy (like estrogen, progesterone, or birth control pills) in the last 3 months.
- You have had a Pap smear in the last 3 years and a mammogram in the last 2 years.
- You are right-handed and comfortable having an MRI scan.
- You have at least some college education and can read and write in English.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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