Clinical trials
Menopause clinical trials
Below are recruiting menopause clinical trials, each written for real people, not researchers. We’re tracking 148 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07511660Enrolling by invitation
Ovarian cell injection for perimenopause symptom relief
This trial tests injecting special cells called Muse cells into the ovaries to help relieve perimenopause symptoms and possibly restore ovarian function. It may help women experiencing irregular periods, hot flashes, sleep problems, mood changes, or trouble thinking clearly.
Monterrey, Nuevo LeónAges 28–70 - NCT06975111RecruitingPhase 2/Phase 3
Improving health during menopause
This trial studies ways to help women during the late menopausal transition. It uses a smartphone app and telehealth visits to track your health and help you feel better.
Aurora, ColoradoAges 45–55 - NCT07022925Recruiting
Wearable device for tracking hot flushes in perimenopause
This study will test if a wearable device can accurately track symptoms like hot flushes and night sweats in women going through perimenopause. If you are between 35 and 55 and experiencing these symptoms, your participation could help improve future symptom monitoring.
London, OntarioAges 35–55 - NCT06530459RecruitingPhase 2/Phase 3
The MUSE Study for Menopausal Joint Pain
This study tests whether a treatment can help women with joint pain and stiffness that started or worsened during menopause. It focuses on women who are within 5 years of menopause and have pain in multiple joints.
SingaporeAges 30–59 - NCT06710002Recruiting
Home program for sexual pain in menopause
This trial tests a home-based therapy program (telerehabilitation) designed to reduce pain during sex and improve sexual function in menopausal women. The program involves exercises and guidance you can do from home without needing to visit a clinic.
Barcelona, SpainAges 45–65 - NCT06982677Recruiting
Improving health in early menopause after cancer
This study looks at ways to improve health and well-being in young women who went into early menopause after cancer treatment. It might help you feel better and manage menopausal symptoms like hot flashes, sleep problems, or mood changes.
Durham, North CarolinaAges 18–44 - NCT07242391Recruiting
Menopausal hormone therapy and heart function study
This study looks at how menopausal hormone therapy might affect the heart's pumping ability. It may help women who are naturally entering menopause understand if hormone therapy can protect their heart health.
Rochester, MinnesotaAges 45–60 - NCT07218445RecruitingPhase 4
Tirzepatide for hot flashes in postmenopausal women with obesity
This study tests whether tirzepatide, a weekly injection, can reduce hot flashes and slow biological aging in postmenopausal women with obesity. It may help if you are experiencing bothersome hot flashes and are willing to follow a diet and exercise plan.
Jacksonville, FloridaAges 46–60 - NCT06678880Recruiting
Sleep and light for mood during menopause
This study tests a program that combines better sleep habits with timed bright light exposure to help improve mood in women going through menopause. It may help reduce the sad or hopeless feelings that often come with this transition.
San Diego, CaliforniaAges 45–75 - NCT06919887Enrolling by invitation
App for women with menopause symptoms
This study tests whether a mobile app can help manage menopause symptoms. You may qualify if you're 45-55, speak English, have menopause symptoms, and have a Mayo Clinic appointment soon.
Rochester, MinnesotaAges 24–80 - NCT06446869Recruiting
Probiotic for menopause symptoms
This study tests whether a probiotic supplement can help reduce hot flashes and other menopause symptoms. It is for women who are in early menopause and have frequent hot flashes.
Glasgow, GlasgowAges 42–60 - NCT07596069Recruiting
Menopause symptoms and physical activity in women 40 to 70
This study looks at how menopause symptoms change during the transition to menopause and whether physical activity affects them. You would fill out an online questionnaire about your symptoms and activity level.
MadridAges 40–70 - NCT07599319Recruiting
Avatar-Based Learning for Spousal Support During Menopause
This study tests whether an interactive computer program with avatars (animated characters) can help spouses better understand and support their partners going through menopause. Both you and your spouse would participate together using digital devices.
BursaAges 45–60 - NCT04439370Recruiting
Blood pressure control study in women with early menopause
This study looks at how the body automatically regulates blood pressure in women who went through menopause earlier than expected. It may help researchers understand whether early menopause affects blood pressure control and related health risks.
Minneapolis, MinnesotaAges 35–70 - NCT04031456RecruitingPhase 2/Phase 3
PRP treatment to help ovaries work again in early ovarian failure
This trial studies whether an injection of your own PRP (platelet-rich plasma) can improve how your ovaries work in people with early ovarian failure. If it helps, it may lead to better hormone balance and return of more regular ovulation and periods.
AthensAges 25–39 - NCT06704516RecruitingPhase 1
HRT and fatty liver disease in menopausal women – a pilot study
This study tests whether starting hormone replacement therapy (HRT) improves liver health in women with menopause and fatty liver disease (MASLD). It aims to understand how HRT might help reduce fat in the liver.
Oxford, OxfordshireAges 18 years+ - NCT06950463Recruiting
Circuit training for bone health after menopause
This trial tests whether a specific exercise program (circuit training) can improve bone density in women after menopause who have low bone mass. It may help strengthen bones and reduce fracture risk.
CairoAges 50–60 - NCT06962345Recruiting
Testing a new vaginal gel for menopause symptoms
This trial is testing a new non-hormonal gel for vaginal dryness and discomfort after menopause. It aims to see if the gel improves quality of life.
Madrid, MadridAges 40–70 - NCT07563621Recruiting
Understanding Vaginal Health Changes in Breast Cancer Survivors
This study examines vaginal dryness and discomfort—common side effects of breast cancer treatment—in women who've survived the disease. Researchers want to understand how often this happens and how much it affects daily life, which may help doctors better support survivors.
Hasselt, LimburgAges 18 years+ - NCT07653620Recruiting
Hydration and women's life stages
This study looks at how hydration affects women at different stages of life (before, during, and after menopause). You'll be asked to exercise, drink certain amounts of water, and sometimes limit fluids so researchers can see how your body responds.
Bradenton, FloridaAges 18–60 - NCT06787066RecruitingEarly Phase 1
Blood vessel study during menopause
This study looks at how blood vessels react to nerve signals during menopause. It may help explain why heart health changes after menopause.
Columbia, MissouriAges 18–70 - NCT06222073Recruiting
How hot flushes affect your skin
This study looks at how hot flushes affect the skin in women before and after menopause. It aims to understand the body changes that cause hot flushes, which may help develop better treatments.
Liverpool, MerseysideAges 18–60 - NCT05672901Recruiting
Silicone gel vs estrogen cream for menopause discomfort
This study compares a silicone gel with an estrogen vaginal cream to treat genital and urinary symptoms caused by menopause. It may help you see which treatment works better and is more comfortable for your symptoms.
Laguna Hills, CaliforniaAges 18 years+ - NCT04757922Enrolling by invitation
Tests whether removing fallopian tubes affects menopause timing
This trial studies whether an “opportunistic salpingectomy” (removing fallopian tubes) during sterilization changes when menopause happens. It compares people who have this procedure to those who get different sterilization (tubal ligation) or none.
EindhovenAges 30–45
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Menopause trials by city
Studies with a site in or near these metro areas.
Menopause trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for menopause?
- Yes. Clin2 currently lists 148 recruiting menopause studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a menopause trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a menopause trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.