Understanding knee pain over time
Part of Bones, joints & muscles, Injuries & trauma clinical trials.
This study follows people with early-stage knee osteoarthritis or past knee injuries to learn what makes knee problems worse over time. It uses questionnaires and basic samples like blood or saliva to track your condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have early-stage knee osteoarthritis (diagnosed, by symptoms, or possible based on NICE guidelines) or had a significant knee injury at age 50 or younger.
- You are willing to provide a blood, synovial fluid, or saliva sample.
- You can read and understand English well enough to complete the study forms and consent.
- You can commit to follow-up for at least 2 years and up to 5 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how knee osteoarthritis or other types of knee arthritis progress over time, using blood tests and X-rays. It aims to find markers that could predict whether the disease will get worse, which may help guide treatment decisions.
This study looks at how knee osteoarthritis (a common condition where the cushioning in the knee joint wears down) affects physical function, even when people report similar levels of pain. It aims to understand why some people with the same pain might have more difficulty with daily activities, which could lead to better targeted treatments.
This study looks at how knee pain from osteoarthritis affects your daily life and health. You'll use a topical anti-inflammatory gel and answer questions by text or email for two months.
This study looks at two substances in your blood that might be linked to knee osteoarthritis. It may help doctors better understand joint damage and could lead to better ways to track the disease.
This study looks at certain enzymes in the blood of women with knee osteoarthritis. It may help doctors understand how arthritis works and could lead to better treatments.
This study follows patients with knee injuries or wear-and-tear arthritis over time to understand how these conditions develop and change. Your health information helps doctors learn what treatments work best and how to prevent problems.
Hear when a new Knee Osteoarthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.