Eye drops for nerve-related eye pain
Part of Eyes & vision, Pain clinical trials.
This study tests an investigational eye drop called urcosimod to see if it can reduce pain from a condition called neuropathic corneal pain, which happens when the nerves in the clear front part of your eye are damaged. If you join, you would use the eye drops for a period and report your pain levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have had eye pain or burning, stinging, or light sensitivity for at least 3 months.
- Your eye pain is 5 or higher on a 0–10 scale (0 = no pain, 10 = worst pain).
- A special eye scan (called IVCM) shows changes in the nerves of the clear front part of your eye (cornea).
- You are willing to use the study eye drops for the duration of the trial.
- You have not had eye surgery in the past 3 months and are not planning any during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new non-invasive treatment (Quantum Molecular Resonance) to see if it can reduce pain and help damaged nerves in the eye heal. It may help people with long-lasting eye pain caused by nerve damage.
This trial tests a new eye drop (acoltre mon) to see if it helps people who have both dry eyes and nerve-related eye pain. The drops may increase tear production and reduce burning or light sensitivity.
This trial tests whether special eye drops made from cord plasma (a blood product) can reduce chronic eye pain caused by damaged nerves in the cornea (the clear front part of your eye). You may qualify if you have had eye pain for at least 3 months without obvious surface damage.
This trial tests an experimental eye drop (STSP-0902) for a condition called neurotrophic keratitis, where the cornea (the clear front part of the eye) gets scratches or sores because nerves are damaged. The drop contains a growth factor to help the eye heal. You might be eligible if you have a persistent scratch or sore on your cornea that has not improved for at least a week.
This trial tests a cooling treatment (EyeCool) for people with long-term pain on the eye's surface. It looks at how the treatment affects the eye's surface structure and inflammation after standard care hasn't worked well enough.
This Phase 2 trial tests BRM424 eye drops in adults with neurotrophic keratitis (a weakened, slow-healing cornea) to see if they help and are safe over 28 days. You may be able to join if your condition matches Stage 2 or Stage 3 and you meet the safety rules.
Hear when a new Neuropathic Corneal Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.