Clin2
NCT07853105Possibly a fitNot yet recruiting

Drug combination for relapsed bone cancers

OsteosarcomasBone CancerEwing Sarcomas

Part of Bones, joints & muscles, Cancer clinical trials.

This trial tests a combination of three drugs (dinutuximab beta, irinotecan, and rapamycin) for people with bone cancers like osteosarcoma or Ewing sarcoma that have come back or not responded to treatment. The goal is to see if this combination can shrink or slow the tumors.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
89 people
Ages
6 years to 40 years
Study type
Interventional

Who can take part

  • You must be between 6 and 40 years old.
  • You must have a type of bone cancer (like osteosarcoma or Ewing sarcoma) that has returned or not responded to treatment.
  • You must have had 1 to 3 prior treatments for your cancer.
  • You must be able to perform daily activities (performance status of 70% or higher).
  • You must not have cancer that has spread to the brain.
  • You must have normal heart, kidney, and liver function, as shown by tests.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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