Paracetamol dosing to prevent shivering after spinal anesthesia for leg surgery
Treatments studied
This study tests different doses of paracetamol (a common pain and fever reducer) to see which one best prevents shivering after spinal anesthesia for lower-limb surgery. Shivering can be uncomfortable, and the study aims to find the safest and most effective dose for patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- Your health status is generally good (classified as ASA I or II).
- You are scheduled for planned (elective) surgery on your lower limb (like the knee, hip, or leg) using spinal anesthesia (numbing injection in your back).
- Your surgery is expected to last between 1 and 3 hours.
- You are willing to give written consent to take part.
- You do not have severely reduced kidney, liver, or thyroid function, a seizure disorder, or a history of alcohol abuse or malnutrition.
- You are not pregnant or breastfeeding.
- You have not taken fever-reducing or anti-inflammatory medication within the last 24 hours.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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