How brensocatib affects a common sedative in healthy adults
Treatments studied
This study tests whether a new drug called brensocatib changes how the body processes midazolam, a medication commonly used for sedation. Healthy adults will take both drugs, and researchers will measure levels in the blood to see if brensocatib affects midazolam.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a healthy adult aged 18 to 65 (based on typical healthy volunteer trials; check with the study team)
- Your body mass index (BMI) is between 18 and 32
- Your blood pressure is within a normal range (systolic 90-140, diastolic 40-90)
- You have normal kidney function
- You have no significant medical conditions (heart, lung, liver, kidney, psychiatric, etc.)
- You are not taking any medications or supplements that could interfere with the study drugs
- You do not have allergies to brensocatib, midazolam, or related substances
- You have not used recreational drugs or alcohol recently (per screening tests)
- You are willing to refrain from blood donation during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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