Treatment
Midazolam clinical trials
We’re tracking 71 recruiting studies that include Midazolam, each written for real people, not researchers, below.
Recruiting studies
- NCT07427446RecruitingPhase 4
Calming drugs for children after heart catheterization
This trial compares two combinations of sedative medicines (dexmedetomidine with midazolam versus ketamine with midazolam) to see which better prevents confusion or agitation when a child wakes up after a heart catheterization procedure. It may help your child recover more calmly.
CairoAges 2–6 - NCT07050095Recruiting
Virtual reality vs. medication for anxiety before eye surgery
This trial compares using a virtual reality headset against a standard anti-anxiety medication (midazolam) to help patients relax before dacryocystorhinostomy (tear duct) surgery. It aims to find a non-drug way to reduce anxiety.
CairoAges 18–65 - NCT07410078Recruiting
Comparing medicines given before surgery for children
This trial compares different medicines given by mouth before surgery to see which works best to help children relax and have less pain. If your child is having day surgery, this study might help find the best pre-surgery medicine for them.
AnkaraAges 4–12 - NCT06330584RecruitingPhase 2
Nasal spray for anxiety in palliative care
This trial tests a nasal spray called midazolam to quickly reduce anxiety in people receiving palliative care. If you're an adult in the hospital with sudden anxiety, this could help you feel calmer.
Basel, Canton of Basel-CityAges 18 years+ - NCT06407518Recruiting
Preoperative medicine for pain relief in colorectal cancer patients with sleep or anxiety issues
This trial tests whether taking a medicine called midazolam before surgery can help with pain after surgery in people with colorectal cancer who have trouble sleeping or feel anxious. You would receive the medicine as a drink before your operation.
Guangzhou, GuangdongAges 18–60 - NCT07340190RecruitingPhase 1
How pelabresib affects other drugs in advanced cancer
This study tests how a new drug (pelabresib) interacts with other medicines like diabetes pills, a sedative, and birth control pills. It is for people with advanced cancer to help understand safe dosing.
BordeauxAges 18 years+ - NCT06692192RecruitingPhase 1
Midazolam and psilocybin for wellbeing study
This trial tests how two different drugs, midazolam and psilocybin, affect the brain and wellbeing. It may help if you feel your wellbeing has dropped a bit but you don't have a diagnosed mood or anxiety disorder.
Madison, WisconsinAges 18–65 - NCT06752759RecruitingPhase 3
Ketamine mist for depression
This trial tests if a ketamine mist you breathe in can help treat moderate to severe depression. It is for adults who are not helped enough by other treatments.
Brooklyn, New YorkAges 18–88 - NCT07502651Enrolling by invitationEarly Phase 1
Comparing two sedatives for jaw fracture surgery
This trial tests two medications given as a nasal spray to help you relax during surgery for a broken jaw. The goal is to see which one works better and is safer.
Rohtak, HaryanaAges 18–50 - NCT07184801RecruitingPhase 3
Comparing two sedatives for medical thoracoscopy
This trial tests if dexmedetomidate or midazolam is safer and works better for sedation during a medical thoracoscopy, a procedure to look inside the chest. It may help you if you need this procedure for an unclear pleural effusion.
Chandigarh, ChandigarhAges 12–90 - NCT07372625RecruitingPhase 1
How rezatapopt affects common drugs in advanced solid tumors with TP53 Y220C mutation
This trial tests how rezatapopt changes the way your body processes four common medicines (metformin, rosuvastatin, repaglinide, and midazolam) in people with advanced solid tumors that have a specific TP53 Y220C gene change. It helps doctors understand the right dose for future patients.
Denver, ColoradoAges 18 years+ - NCT07013955Enrolling by invitationPhase 3
Comparing nasal packing drugs for better sinus surgery view
This trial is testing whether packing the nose with one of three medications (dexmedetomidine, midazolam, or bupivacaine) during functional endoscopic sinus surgery (FESS) can improve the surgeon's view during the procedure. It may help patients by reducing bleeding and making the surgery smoother.
MinyaAges 16–60 - NCT06878703RecruitingPhase 3
Dexmedetomidine vs midazolam for preterm babies on a ventilator
This study compares two sedative medicines, dexmedetomidine and midazolam, to see which one helps preterm babies on a ventilator breathe on their own sooner. Your baby may be eligible if they were born very early and need medicine to relax while on the breathing machine.
ParisAges Up to 7 months - NCT06614036RecruitingPhase 4
Remimazolam vs. Midazolam for sedation during upper GI endoscopy
This study compares two different sedative medicines, remimazolam and midazolam, to see which works better for people having a routine upper GI endoscopy (a camera test to look at your stomach and esophagus). If you are scheduled for this procedure and need sedation, you may be able to join.
Apeldoorn, GelderlandAges 18 years+ - NCT05160987Recruiting
Sedation choice for ICU patients on breathing machines
This study compares two sedation medicines—remimazolam vs midazolam—for very sick ICU patients who are on a breathing machine. It looks at whether one sedative works better or is safer for keeping patients comfortable while they’re critically ill.
Guangzhou, GuangdongAges 18–80 - NCT05313308Recruiting
Survey of midazolam use in non-convulsive seizure emergencies
This trial is a survey about how midazolam is used in people with non-convulsive status epilepticus, especially when it’s given outside a medical facility and when an extra dose is needed. It may help doctors better understand real-world treatment patterns and safety.
TokyoAges Any age - NCT05371886Recruiting
Testing how morphine (with or without midazolam) behaves in NICU babies
This study measures how morphine works in very young babies, and whether adding midazolam changes how the medicines behave and affect the body. It may help doctors better choose and dose pain/sedation medicines for babies in intensive care.
BrestAges 5 months–10 months - NCT05934669RecruitingPhase 4
Numbing medicines compared for small stitches in young children
This trial tests three medicines given through the nose to keep children comfortable during minor procedures in the emergency department, specifically for closing small cuts with stitches. It may help find which nasal medicine works best and is safest for quick, minimal procedures.
Oklahoma City, OklahomaAges 1–5 - NCT06480500RecruitingPhase 2
Online therapy and IV ketamine for severe depression with suicide risk
This study tests whether adding an online therapy (i-CBT) to intravenous (IV) ketamine is better than IV ketamine alone for people with treatment-resistant depression who are also thinking about suicide. You'll receive either ketamine or a comparison drug (midazolam), plus the online therapy, in a hospital setting.
Toronto, OntarioAges 21–65 - NCT06638710RecruitingPhase 2
Testing oral midazolam for care in elderly with dementia who refuse care
This trial tests if giving a medication called midazolam by mouth can help older adults with memory problems who refuse care to accept it more calmly. It is for people in certain hospital or long-term care units, with moderate to severe memory loss and a history of resisting care.
Grenoble, IsereAges 60 years+ - NCT06926413RecruitingPhase 1
How aumolertinib changes midazolam levels in lung cancer patients
This study tests how a lung cancer pill called aumolertinib affects the levels of another drug (midazolam) in your body. It is for people with advanced NSCLC whose tumors have specific EGFR gene changes.
Hangzhou, ZhejiangAges 18 years+ - NCT07113483RecruitingPhase 3
Remimazolam vs. Midazolam for sedation in older adults having orthopedic surgery
This trial compares two sedatives, remimazolam and midazolam, to see which one leads to better recovery of thinking skills after orthopedic surgery. It is for people aged 65 and older who are having surgery on a bone or joint while awake but relaxed.
BucharestAges 65 years+ - NCT07331389RecruitingPhase 1
How HDM1002 interacts with common drugs and diabetes medications
This study tests how a new drug called HDM1002 interacts with common diabetes medications (metformin, empagliflozin) and other drugs like warfarin and valsartan. If you are a generally healthy adult (age 18-45) with a higher BMI, this trial helps ensure the new drug is safe when taken with other medicines.
HefeiAges 18–45 - NCT07357610RecruitingPhase 1
Drug interaction study of SIM0270 in healthy adults
This trial tests how SIM0270 interacts with other drugs (itraconazole, rifampin, midazolam) in healthy Chinese adults. It helps doctors understand if SIM0270 is safe and how it works in the body.
Jinan, ShandongAges 18–55
What Midazolam is being studied for
Conditions with recruiting Midazolam studies.
Common questions
- Are there clinical trials studying Midazolam?
- Yes. Clin2 currently lists 71 recruiting studies that include Midazolam, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Midazolam trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Midazolam an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Midazolam or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.