Cartilage repair for large ear drum holes in children
Part of Brain & nervous system, Ear, nose & throat, Injuries & trauma clinical trials.
This study tests a surgery that uses a small piece of cartilage to close large holes in the eardrum of children. It aims to improve hearing and reduce the risk of the hole coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 8 and 18 years old.
- You have a large hole in your eardrum that has been there for at least 6 months.
- The hole has been dry (no active infection or drainage) for at least 6 months.
- You have hearing loss caused by the hole in your eardrum.
- You are able to complete hearing tests before and after surgery.
- Your parent or guardian must agree to the surgery, and you must agree if appropriate.
- You do not have a cholesteatoma (a skin cyst in the middle ear), an active ear infection, or other ear problems that would affect the surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new way to fix a hole in the eardrum using a curved piece of cartilage. It aims to improve the success of the surgery for a specific type of eardrum hole.
This trial tests whether adding an extra layer of connective tissue (fascia) during eardrum repair improves results for people with large holes in their eardrum. It may help reduce the chance of the hole coming back and improve hearing.
This study looks at Tympanoseal for people who still have a childhood ear tube or a small eardrum hole. It may help protect the ear and improve healing, while researchers compare outcomes using a standardized approach.
This study compares two ways to help a small hole in the eardrum close: using a chemical (silver nitrate) to encourage healing, versus just watching and waiting. If you have a small, dry hole in one eardrum that has not healed on its own, this trial may help you find a treatment that could improve your hearing.
This trial tests a special gel applied during common ear surgeries to see if it helps healing and improves hearing. It may be an option for people having surgery to fix a perforated eardrum, repair ear bones, or treat chronic ear infections.
This research study tests a new way to measure how well your middle ear (the tiny bones behind your eardrum) works using sound waves instead of traditional hearing tests. It involves three groups: people with normal hearing, people with conductive hearing loss, and people scheduled for cochlear implant surgery.
Hear when a new Tympanic Membrane Perforation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.