How artificial sweeteners affect blood sugar in prediabetes
Part of Hormones & metabolism clinical trials.
This study looks at how non-nutritive sweeteners (like aspartame or sucralose) affect blood sugar levels in people with prediabetes. It aims to see if these sweeteners change gut bacteria and, in turn, blood sugar control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have prediabetes, with an HbA1c between 5.7% and 6.4% (a recent blood test within the last 6 months)
- You are 35 years or older and have a body mass index (BMI) of 25 or higher
- Your kidney function is adequate (eGFR of at least 45 on a recent test)
- You rarely use artificial sweeteners (less than once a week)
- You do not have diabetes, have not had weight-loss surgery or an organ transplant, and are not taking certain medications (like metformin, GLP-1 agonists, or steroids)
- You are not pregnant or breastfeeding and have no severe gastrointestinal disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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