Preventing COPD flare-ups with an inhaled study drug
Part of Lungs & breathing clinical trials.
This study tests an inhaled medication called ensifentrine to see if it can prevent flare-ups (exacerbations) in people with COPD who have had at least one moderate or severe flare-up in the past year while on their current treatment. If you qualify, you may receive the study drug or a placebo, and your COPD symptoms and flare-ups will be closely monitored.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with COPD for at least 1 year.
- You are on a stable treatment with specific inhalers (LAMA/LABA with or without ICS) for at least 2 months before starting the study.
- You have had at least 1 moderate or severe COPD flare-up in the past year while on your current inhalers.
- You are a current or former smoker with a smoking history of at least 10 pack-years (e.g., 1 pack a day for 10 years, or half a pack a day for 20 years).
- Your lung function (FEV1) is between 25% and 70% of the predicted normal value after using a bronchodilator.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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