Comparing two muscle-cutting methods for achalasia treatment
Part of Digestive system clinical trials.
This study compares two ways of doing a surgery called POEM to treat achalasia, a condition where the esophagus doesn't empty properly. The surgery cuts the muscle at the lower end of the esophagus to help food pass more easily. The trial will see if cutting the muscle partially works as well as cutting it all the way through.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have achalasia, confirmed by a special test that measures how your esophagus squeezes (manometry)
- You have type 1 or type 2 achalasia (but not type 3)
- You have an Eckardt score above 3, meaning you have significant symptoms like trouble swallowing, chest pain, or regurgitation
- You are healthy enough to receive anesthesia for the surgery
- You do not have a hiatus hernia (where part of the stomach pokes up into the chest)
- You do not have a bleeding disorder (coagulopathy)
- You do not have other esophagus muscle disorders
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two types of electrical tools used during a POEM procedure to treat swallowing problems. It aims to find which tool works better for patients with esophageal motility disorders.
This trial compares two ways to help children with achalasia (a condition where the esophagus muscle doesn't relax, making it hard to swallow). It tests if inflating a balloon or using a thin tube to cut the muscle works better. If your child qualifies, they may get one of these treatments to help them eat more easily.
This study tests a procedure called POEM-F for achalasia types I–II or III. It may help people who haven't had treatment or who've had balloon dilation before.
This trial looks at people who had a procedure called POEM for achalasia and want to understand outcomes after that treatment. If you’re an adult and already had POEM for achalasia, you may be able to join.
This is a study that collects information in a research database for adults with achalasia who are referred for POEM, a procedure to help food move more easily. It may help researchers understand outcomes and care for people with achalasia.
This trial studies how well POEM and other endoscopy-based (through-the mouth) treatments work for conditions like acid reflux, achalasia (trouble moving food), and Barrett’s esophagus. It may help doctors compare outcomes and choose the safest, most effective procedure for your situation.
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