Comparing antibiotics and placebo for children with ear infection
Treatments studied
Part of Ear, nose & throat clinical trials.
This study tests whether amoxicillin-clavulanate, amoxicillin, or a placebo (a pill with no medicine) works best for children with acute otitis media, which is a middle ear infection. The goal is to find the safest and most effective way to treat this common childhood illness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must have symptoms like fever, ear pain, or cold symptoms, plus signs of a middle ear infection seen by a doctor.
- The doctor must see redness or bulging of the eardrum and fluid behind the eardrum.
- Your child must not have a severe ear infection complication like mastoiditis, facial weakness, or inner ear infection.
- Your child must not have a known allergy to amoxicillin or other penicillin-like antibiotics.
- Your child must not have taken antibiotics for another infection within the past two weeks, and must not have ear tubes or a long-standing eardrum hole.
- Your child must not have immune system problems, severe kidney disease, or a known hearing defect.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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