Clinical trials
Actinic Keratoses clinical trials
Below are recruiting actinic keratoses clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06851507RecruitingPhase 3
Comparing two creams for multiple actinic keratoses
This study compares a cream with fluorouracil alone to a cream with fluorouracil plus calcipotriene for people with several actinic keratoses (a type of rough, precancerous spot caused by sun damage). The goal is to see if the combination works better.
Houston, TexasAges 18 years+ - NCT06274320Recruiting
Testing a urea cream before actinic keratosis treatment
This trial tests whether applying a 30% urea cream (Lipikar) before Tolak® treatment helps treat actinic keratoses (rough, scaly spots) on the scalp. It may make the skin more receptive to the treatment.
WuppertalAges 18 years+ - NCT07401277RecruitingPhase 1
5-FU plus aluminum for actinic keratoses on scalp or forearms
This trial tests whether a combination of the chemotherapy cream 5-fluorouracil and an aluminum solution works well to treat actinic keratoses (precancerous sun-damaged spots) on the scalp or forearms. It may help if you have 4–15 of these spots and are generally healthy.
Morgantown, West VirginiaAges 18–50 - NCT07335003Recruiting
Sunscreen study for preventing skin damage in older adults with actinic keratoses
This study tests a new sunscreen (Anthelos Fluide 100 KA+ UVMune 400) to see if it can protect skin and prevent further sun damage in people who already have multiple actinic keratoses (precancerous spots). It may help reduce the risk of new spots or skin cancer.
Camperdown, New South WalesAges 60 years+ - NCT06321003Recruiting
Testing AI to detect early oral cancer with light scans
This trial uses a special light-based scanner (OCT) and artificial intelligence to help diagnose early signs of mouth cancer or precancer. It aims to see if this combination can make diagnosis easier and more accurate.
PalermoAges 18–99 - NCT03906253Recruiting
Laser treatment to prevent skin growth in older adults
This trial tests whether a type of laser treatment can help protect older adults’ skin from turning actinic keratosis (a sun-related precancer) into more serious skin problems. It focuses on the forearms and may help reduce future skin damage while checking safety and comfort.
Dayton, OhioAges 60 years+ - NCT06499415RecruitingPhase 4
Combination cream vs standard cream for precancerous skin spots
This trial tests if adding calcipotriol to a standard chemotherapy cream (5-fluorouracil) works better than the standard cream alone for treating actinic keratosis (precancerous sun-damaged skin spots). You may qualify if you have at least four spots on your face, scalp, neck, chest, or arms.
Heerlen, LimburgAges 18 years+ - NCT06461442Enrolling by invitationPhase 4
Freezing vs. cream for sun-damaged spots
This study compares two ways to treat sun-damaged spots called actinic keratoses: freezing them (cryotherapy) or applying a chemotherapy cream (5-fluorouracil). The goal is to see which works better and is safer for people with many spots on their head, neck, arms, or legs.
Sacramento, CaliforniaAges 18 years+ - NCT06648447Recruiting
Testing tirbanibulin cream for certain actinic keratoses
This study tests whether tirbanibulin (Klisyri) cream works well on specific types of actinic keratosis on the scalp or face that have a downward growth pattern. It helps doctors understand if this treatment is right for those skin spots.
Wuppertal, North Rhine-WestphaliaAges 18 years+ - NCT06428721Recruiting
Can laser treatment prevent skin spots in older adults?
This study tests if a laser treatment on your forearms can prevent precancerous spots (actinic keratoses) from developing in older adults with fair skin. You would receive the laser on one arm and a sham treatment on the other, and your skin will be monitored.
Fairborn, OhioAges 60 years+ - NCT06385340Recruiting
Testing Lipikar Baume AP+M for actinic keratosis
This study tests if a moisturizing cream called Lipikar Baume AP+M can help with actinic keratoses (rough, scaly spots caused by sun damage) on the forearms or backs of the hands. You'll use the cream on one arm and compare it to the other arm to see if it makes a difference.
Wuppertal, North Rhine-WestphaliaAges 18 years+
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Common questions
- Are there clinical trials for actinic keratoses?
- Yes. Clin2 currently lists 11 recruiting actinic keratoses studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a actinic keratoses trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a actinic keratoses trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.