Freezing vs. cream for sun-damaged spots
Treatments studied
Part of Cancer, Skin clinical trials.
This study compares two ways to treat sun-damaged spots called actinic keratoses: freezing them (cryotherapy) or applying a chemotherapy cream (5-fluorouracil). The goal is to see which works better and is safer for people with many spots on their head, neck, arms, or legs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You have at least 10 sun-damaged spots (actinic keratoses) on your head, neck, arms, or legs
- You have not had any treatment for these spots in the last 2 months
- You are not pregnant or breastfeeding
- You do not have a weakened immune system or an allergy to the study drugs or peanut/soy products
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a two-step treatment for actinic keratosis (rough, scaly patches from sun damage) on the scalp and forehead. First, the patches are frozen (cryotherapy), then a medicated ointment (tirbanibulin) is applied. The goal is to see if this combination is safe and works better than freezing alone.
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