Freezing vs. cream for sun-damaged spots
Treatments studied
Part of Cancer, Skin clinical trials.
This study compares two ways to treat sun-damaged spots called actinic keratoses: freezing them (cryotherapy) or applying a chemotherapy cream (5-fluorouracil). The goal is to see which works better and is safer for people with many spots on their head, neck, arms, or legs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You have at least 10 sun-damaged spots (actinic keratoses) on your head, neck, arms, or legs
- You have not had any treatment for these spots in the last 2 months
- You are not pregnant or breastfeeding
- You do not have a weakened immune system or an allergy to the study drugs or peanut/soy products
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if adding calcipotriol to a standard chemotherapy cream (5-fluorouracil) works better than the standard cream alone for treating actinic keratosis (precancerous sun-damaged skin spots). You may qualify if you have at least four spots on your face, scalp, neck, chest, or arms.
This trial tests whether a combination of the chemotherapy cream 5-fluorouracil and an aluminum solution works well to treat actinic keratoses (precancerous sun-damaged spots) on the scalp or forearms. It may help if you have 4–15 of these spots and are generally healthy.
This trial tests whether freezing the spots (cryotherapy) followed by a medicated ointment (tirbanibulin) works better than freezing alone for actinic keratoses on the scalp and forehead. It may help you if you have many of these rough spots and want to see if the combination treatment works better.
This trial compares two different creams used before a light-based treatment (photodynamic therapy) for actinic keratoses on the scalp. It aims to see which pre-treatment works better to clear these rough, scaly spots.
This Phase 2 study compares two treatments to clear actinic keratoses (sun-caused pre-cancer skin spots) on the upper arms. If you qualify, you may get one of the study treatments and contribute to finding which one works best and is easiest to use.
This study tests if a moisturizing cream called Lipikar Baume AP+M can help with actinic keratoses (rough, scaly spots caused by sun damage) on the forearms or backs of the hands. You'll use the cream on one arm and compare it to the other arm to see if it makes a difference.
Hear when a new Actinic Keratoses trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.