Clinical trials
Adolescent clinical trials
Below are recruiting adolescent clinical trials, each written for real people, not researchers. We’re tracking 954 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05164172RecruitingPhase 3
Eptinezumab for kids with ongoing or recurring migraine
This trial studies eptinezumab, a migraine treatment, in children and teens ages 6 to 17 who already completed an earlier migraine study. It mainly helps doctors learn whether the treatment can be continued safely and effectively over time.
New Haven, ConnecticutAges 6–17 - NCT05210907RecruitingPhase 1
Hospital-made CD19 CAR-T for relapsed leukemia in children
This Phase 1 study tests a homemade (hospital-manufactured) immune treatment called CD19 CAR-T for children and teens with a type of leukemia that has come back or did not respond. It may help by targeting leukemia cells that carry the CD19 marker.
SeoulAges birth–25 years - NCT05275881Recruiting
Virtual reality during procedures for young blood or cancer patients
This trial tests whether using virtual reality (VR) during certain procedures can make them easier for children, teens, and young adults with blood or cancer-related conditions. Participants must be able to safely use a VR headset and be willing to take part.
PoitiersAges 7–24 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT05286151Recruiting
Studying brain connectivity and timing in stuttering and nonstuttering teens
This study looks at how brain “networks” connect and how timing works in adolescents who stutter compared with those who don’t. It may help researchers better understand what underlies stuttering and how it differs from typical speech timing.
Ann Arbor, MichiganAges 9–13 - NCT05295680RecruitingPhase 2
Oral hymecromone for primary sclerosing cholangitis
This trial tests whether taking hymecromone by mouth can improve primary sclerosing cholangitis (a liver/bile duct condition). It may help by targeting inflammation and bile duct problems, especially in people who are stable on other medicines.
Redwood City, CaliforniaAges 14–75 - NCT05304286Recruiting
Study of brain and pain in long-lasting post-surgery pain
This trial studies what’s happening in the brain and how pain is processed in people with pain that lasts long after surgery. It may help researchers understand chronic post-surgical pain and find better ways to treat it.
Boston, MassachusettsAges 12 years+ - NCT05304988Recruiting
Exercise therapy program for teens with cancer
This study is developing and testing (validating) an “exercise-focused” therapy for teenagers with cancer. It may help researchers see whether this approach is practical and beneficial, especially for teens’ communication and activity support.
Hong Kong, Hong Kong,ChinaAges 13–18 - NCT05310591RecruitingPhase 1/Phase 2
Study anti-PD1 treatment with Kymriah re-dosing for leukemia
This Phase 1/2 trial studies giving an anti-PD1 antibody (like pembrolizumab or nivolumab) along with a second Kymriah (tisagenlecleucel) infusion in children and young adults whose B-cell leukemia is coming back or their Kymriah effect has faded. It may help the new immune treatment work better after the first Kymriah.
BordeauxAges 1–25 - NCT05334823RecruitingPhase 2
CAR T-cell treatment for CD19-positive relapsed leukemia in children
This Phase 2 trial tests pCAR-19B, a customized immune-cell treatment for children and teens with CD19-positive B-ALL that has come back or did not respond to standard therapy. If eligible, you would receive the cell infusion after cell collection and testing to make sure the leukemia cells have the right marker.
Beijing, Beijing MunicipalityAges 3–21 - NCT05336084Recruiting
Study how sleep timing affects mood and thinking in teens
This study looks at how your body clock and sleep “pressure” affect reward feelings and thinking control. It may help researchers understand teen sleep patterns and how they connect to brain and behavior.
Pittsburgh, PennsylvaniaAges 13–18 - NCT05336201RecruitingPhase 2
Brain training program for teens with sickle cell disease
This Phase 2 study tests a cognitive (thinking) training program to help teens with sickle cell disease prepare for the changes in their care as they grow older. It may help with skills like learning, attention, and planning for transition to adult care.
Birmingham, AlabamaAges 10–18 - NCT05336318Recruiting
Peer support program for young people after cancer
This trial studies a peer-to-peer support program, where young cancer survivors support others who are newly diagnosed. It may help by improving emotional support and coping while you go through cancer treatment and recovery.
Leipzig, SaxonyAges 18–39 - NCT05337033RecruitingPhase 2
Testing cannabis for chronic headaches in teens
This trial studies whether cannabis can reduce chronic migraine headaches in adolescents who have not improved with other treatments. It also asks participants to work with psychology and physiotherapy during the study.
Vancouver, British ColumbiaAges 14–17 - NCT05383911Recruiting
Sickle cell care plan choices for teens and young adults
This trial tests a way to help teens and young adults with sickle cell disease (SCD) and their caregivers actively take part in treatment decisions. It focuses on improving shared decision-making through interviews and a partner-centered approach.
Wilmington, DelawareAges 15 years+ - NCT05383742RecruitingPhase 2
Compare 6- vs 9-month treatment for tuberculous meningitis
This Phase 2 study tests whether a shorter, stronger 6-month set of medicines works as well as the usual 9-month regimen for tuberculous meningitis (TB infection in the covering of the brain/spinal cord). The goal is to improve outcomes while reducing treatment time and exposure.
Porto AlegreAges 15 years+ - NCT05390268Recruiting
Mobile app behavioral therapy for youth with tic disorders
This trial tests whether a mobile app can help children and teens reduce tic symptoms using behavioral treatment strategies. It may help if your tics are affecting your daily life and you have not had very recent tic-specific behavioral training.
Aarhus N, RisskovAges 9–17 - NCT05390918Recruiting
Trial for teen sleep and suicidal thoughts risk
This study aims to see if treating insomnia (sleep problems) can lower overall risk related to suicidal behavior in teens. You may be eligible if you’ve had both recent sleep issues and recent suicidal thoughts, with some important safety exclusions.
Columbus, OhioAges 11–18 - NCT05413278Recruiting
Helps teens with inherited metabolism conditions move to adult care
This study tests a targeted approach to help teenagers with inherited metabolism conditions successfully transfer from children’s to adult healthcare. It may help families feel more confident and reduce problems during the handoff to adult services.
ViennaAges 14–25 - NCT05427123Recruiting
Study for kids and teens with bipolar or cyclothymic disorder
This trial is testing treatments for children and teens (ages 9–19) who have been diagnosed with bipolar disorder or cyclothymic disorder. It also requires regular participation from a caregiver so the team can track symptoms and response over time.
Los Angeles, CaliforniaAges 9–19 - NCT05443737RecruitingPhase 3
Telehealth care to protect fertility in young people with cancer
This trial tests a telehealth (video/phone) program that helps adolescents and young adults with cancer plan for future fertility. It may help you get support and options for preserving your ability to have children before cancer treatment affects it.
Duarte, CaliforniaAges birth–50 years - NCT05492032Recruiting
Brain stimulation sessions for teens with autism symptoms
This trial tests whether repeated, brain-based stimulation (done through the scalp) can improve symptoms in adolescents with autism spectrum disorder, and whether a later “booster” session adds more benefit. It may help learn which stimulation schedule works best, especially when teens also have attention symptoms—but not epilepsy or mood/anxiety disorders.
Hung Hom, KowloonAges 12–21 - NCT05518383RecruitingPhase 4
Pediatric B-cell lymphoma treatment study using established care
This trial studies treatment for children and teens with certain B-cell non-Hodgkin lymphomas using a specific treatment protocol. It may help doctors confirm how well the regimen works in young patients and improve care over time.
Moscow, RFAges 1 day–18 years - NCT05563649Recruiting
Online guided family self-help for teens with anorexia
This trial tests whether an online, guided “self-help” program that involves the family helps teens with anorexia recover better than usual care. It aims to improve eating and reduce anorexia symptoms while being delivered from home.
Stanford, CaliforniaAges 12–18
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Common questions
- Are there clinical trials for adolescent?
- Yes. Clin2 currently lists 954 recruiting adolescent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adolescent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adolescent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.