Clinical trials
Adolescent clinical trials
Below are recruiting adolescent clinical trials, each written for real people, not researchers. We’re tracking 957 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05413278Recruiting
Helps teens with inherited metabolism conditions move to adult care
This study tests a targeted approach to help teenagers with inherited metabolism conditions successfully transfer from children’s to adult healthcare. It may help families feel more confident and reduce problems during the handoff to adult services.
ViennaAges 14–25 - NCT05427123Recruiting
Study for kids and teens with bipolar or cyclothymic disorder
This trial is testing treatments for children and teens (ages 9–19) who have been diagnosed with bipolar disorder or cyclothymic disorder. It also requires regular participation from a caregiver so the team can track symptoms and response over time.
Los Angeles, CaliforniaAges 9–19 - NCT05443737RecruitingPhase 3
Telehealth care to protect fertility in young people with cancer
This trial tests a telehealth (video/phone) program that helps adolescents and young adults with cancer plan for future fertility. It may help you get support and options for preserving your ability to have children before cancer treatment affects it.
Duarte, CaliforniaAges birth–50 years - NCT05492032Recruiting
Brain stimulation sessions for teens with autism symptoms
This trial tests whether repeated, brain-based stimulation (done through the scalp) can improve symptoms in adolescents with autism spectrum disorder, and whether a later “booster” session adds more benefit. It may help learn which stimulation schedule works best, especially when teens also have attention symptoms—but not epilepsy or mood/anxiety disorders.
Hung Hom, KowloonAges 12–21 - NCT05518383RecruitingPhase 4
Pediatric B-cell lymphoma treatment study using established care
This trial studies treatment for children and teens with certain B-cell non-Hodgkin lymphomas using a specific treatment protocol. It may help doctors confirm how well the regimen works in young patients and improve care over time.
Moscow, RFAges 1 day–18 years - NCT05563649Recruiting
Online guided family self-help for teens with anorexia
This trial tests whether an online, guided “self-help” program that involves the family helps teens with anorexia recover better than usual care. It aims to improve eating and reduce anorexia symptoms while being delivered from home.
Stanford, CaliforniaAges 12–18 - NCT05588648RecruitingPhase 1/Phase 2
Testing vactosertib for osteosarcoma that keeps coming back
This Phase 1/2 study tests how safe and how well vactosertib works for adolescents and adults with osteosarcoma that has returned, stopped responding, or is getting worse despite prior treatment. You may be able to join if you meet age, cancer, recovery-from-prior-therapy, and health-test requirements.
Cleveland, OhioAges 12 years+ - NCT05608551Recruiting
Animal-assisted therapy for children after trauma
This study tests a therapy program that uses animals to help children and teens who have had a traumatic event and still have post-traumatic stress symptoms. The goal is to see if this approach can reduce distressing symptoms and improve coping.
BaselAges 9–17 - NCT05617495Recruiting
Mindfulness training with brain scans for depression
This study tests a mindfulness-based program combined with “brain scan feedback” (fMRI neurofeedback) to see if it can help teenagers and young adults with major depression. It may help by teaching skills and tracking brain activity changes during treatment.
Boston, MassachusettsAges 13–18 - NCT05638724Recruiting
Long COVID health registry for people of all ages
This study builds a health registry to learn how long COVID affects children, teens, and adults over time. It may help by improving understanding of symptoms and care, even if it does not test a new drug.
Munich, BavariaAges Any age - NCT05648591RecruitingPhase 4
Iloperidone study for teens with schizophrenia or bipolar I
This Phase 4 study checks how safe and well-tolerated iloperidone is when used in a typical, open-label way for teenagers. It may help doctors better understand side effects and safety in teens with schizophrenia or bipolar I disorder.
Little Rock, ArkansasAges 12–17 - NCT05654012Recruiting
Study of migraine risk in teens and kids
This study looks at how migraine may start or affect children by comparing young people who either have migraine symptoms or are at higher risk. It may help researchers understand migraine patterns and who could benefit from early prevention.
St Louis, MissouriAges 10–13 - NCT05660473RecruitingPhase 2
Study of venetoclax plus chemotherapy for Ph-negative ALL
This Phase 2 trial tests whether adding venetoclax to a chemotherapy plan works better for Philadelphia chromosome–negative acute lymphoblastic leukemia (ALL). It may help people achieve deeper remission by targeting leukemia cells in a different way than chemotherapy alone.
TianjinAges 14–60 - NCT05666986Recruiting
Sports and activity check-in for teens after diaphragmatic hernia surgery
This study looks at how adolescents who had diaphragmatic hernia surgery as babies engage in physical activities and sports. It will use questionnaires and an optional interview by video call to learn what helps or gets in the way—so care teams can better support families.
LilleAges 12–18 - NCT05667506RecruitingPhase 1/Phase 2
Check CNCT19 cell therapy for relapsed childhood ALL
This early-stage trial tests a personalized immune-cell treatment called CNCT19 in children and teens whose leukemia (ALL) has come back or not responded to prior therapy. It may help the immune system recognize and attack leukemia cells that carry CD19.
Hefei, AnhuiAges 3–18 - NCT05677412Recruiting
Studying sleep, stress, and pain in teens with ongoing pain
This study looks at how sleep and stress relate to pain that keeps coming back in teens. It may help researchers understand what could improve comfort and daily functioning when pain lasts more than three months.
HelsinkiAges 15–17 - NCT05685368RecruitingPhase 1/Phase 2
Therapy groups to help teens cope with sickle cell
This trial tests a structured talk-therapy program called Acceptance and Commitment Therapy (ACT) for teens and young adults with sickle cell disease. It aims to help you manage tough thoughts and feelings and cope with day-to-day challenges over 6 weekly group sessions.
Los Angeles, CaliforniaAges 14–21 - NCT05707975Recruiting
Support for teens with eco-anxiety and suicidal thoughts
This trial studies a program to help adolescents who feel eco-anxiety (distress about environmental issues) and may also be at risk for suicidal thoughts. It may help by testing an approach for teens during a hospital stay in child mental health care.
Bron, RhoneAges 12–16 - NCT05709132Recruiting
Peer mentorship program for teens living with heart failure
This program matches teens (ages 12–17) with a trained young adult mentor to exchange supportive check-ins by text or phone over about 15 weeks. It aims to help teen patients better manage their heart condition and feel supported through their care.
Toronto, OntarioAges 12–30 - NCT05709470Recruiting
Mental health support study for children with heart defects
This study looks at mental health in children and teens (age 5–17) who were born with a heart defect. It may help researchers understand what support is needed and how best to measure mental well-being.
CopenhagenAges 5–17 - NCT05719246Recruiting
Yoga and meditation for teens with IBS stress
This study tests a structured yoga and meditation program to help reduce stress symptoms in teens with irritable bowel syndrome (IBS). It may help your teen learn calming practices that could ease how stress affects IBS.
Camden, New JerseyAges 12–21 - NCT05740254Recruiting
Compare early versus late eating times for teen obesity
This study tests whether having a shorter daily eating schedule earlier in the day works better than a later eating schedule for reducing weight and improving health in teens with obesity. Participants will also follow planned fasting (not eating) periods and complete regular check-ins.
Los Angeles, CaliforniaAges 12–21 - NCT05754632Recruiting
Blood flow restriction exercises after ACL surgery in teens
This trial tests whether a special type of exercise that uses a cuff (blood flow restriction training, or BFRT) can help teens recover after ACL reconstruction. It’s designed to see if adding BFRT to standard rehab improves strength and return to sport.
Farmington, ConnecticutAges 12–18 - NCT05763849Recruiting
Therapy exposure for teens with low weight eating issues
This trial tests a structured therapy approach called “interoceptive exposure” for teens who have an eating disorder with low weight. It may help some teens reduce fear or avoidance around body sensations and improve eating, but you must meet several health and safety criteria.
New York, New YorkAges 12–18
Hear when a new Adolescent trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for adolescent?
- Yes. Clin2 currently lists 957 recruiting adolescent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adolescent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adolescent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.