ActiveGirls: Activity, hormones, and diabetes risk in young girls
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study looks at how physical activity and hormone health affect diabetes risk in young girls. It is for girls ages 8 to 12 who are at risk for PCOS (a hormone condition) and insulin resistance, and who have not yet started their period.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must be a girl between 8 and 12 years old who has not yet started her period.
- Your child must be able to speak and understand English.
- Your child must have at least one of these risk factors: a mother with PCOS or gestational diabetes, a BMI at or above the 85th percentile, early signs of puberty, or being born small for gestational age.
- A caregiver (parent or legal guardian) must speak English and have access to a phone or computer for study messages.
- Your child cannot be taking certain medications for diabetes or hormone issues, or have conditions like type 1 or type 2 diabetes, thyroid problems, or other serious health problems that limit physical activity.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how eating or daily habits that promote weight gain (“obesogenic” lifestyle) affect fitness and health markers in young adults who already exercise. It may help researchers understand what lifestyle changes matter most, and whether certain patterns affect active people differently.
This study looks at how well the body uses insulin (insulin sensitivity) across different ages, sexes, races, body weights, and whether someone has PCOS. It may help researchers understand why insulin function varies and how PCOS could be linked to metabolic health.
This early study looks at how certain “male-type” hormones and brain signals (measured through hormone patterns during the day and night) work in adolescent girls with high androgen levels. It may help researchers better understand causes like PCOS and related hormone timing differences.
This study tests how the body handles sugar (glucose) in women with a specific type of PCOS. It compares responses between women with PCOS and those without to understand metabolic changes.
This study looks at differences in ovarian structure and related hormone or metabolic patterns in adolescent girls soon after their first period. It may help researchers better understand early changes that can be linked to conditions like PCOS (polycystic ovary syndrome).
This trial tests whether a combination of coaching (cognitive-behavioral therapy) and exercise can improve mood and help teens who are at higher risk for type 2 diabetes. It may be especially helpful if you’re dealing with depression symptoms and a family history of type 2 diabetes.
Hear when a new Puberty trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.