Descartes-08 for young people with autoimmune diseases
Part of Bones, joints & muscles, Brain & nervous system, Heart & circulation, Immune system & allergy, Skin clinical trials.
This trial tests a new therapy called Descartes-08 for children, teens, and young adults with autoimmune conditions like lupus, myasthenia gravis, or dermatomyositis. It aims to see if it can help control moderate disease that hasn't responded well enough to other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 12 years old
- You have been diagnosed with childhood-onset lupus, juvenile myasthenia gravis, juvenile dermatomyositis, or certain types of vasculitis (AAV)
- Your disease is moderate in severity and you have tried other treatments before
- You or your parent/guardian can understand and sign a consent form
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new CAR-T cell therapy that targets two proteins (CD19 and BCMA) on immune cells. It's designed for people with certain autoimmune diseases like lupus, scleroderma, vasculitis, myositis, or Sjögren's syndrome that are not controlled by standard treatments.
This trial tests a new treatment (YTS109) for children with certain autoimmune diseases that have not responded to standard therapies. The treatment targets B cells, which are part of the immune system, to help calm down the immune attack.
This trial tests a new type of immune therapy called CAR T-cells that target two markers on your B cells (CD19 and BCMA). It is for people with certain autoimmune diseases that have not improved or have come back after standard treatments. The goal is to see if this therapy can help control the disease.
This trial tests a special type of cell therapy (CAR T-cells) that targets two markers on immune cells, CD19 and BCMA, to calm overactive immune systems in people with certain autoimmune diseases. It's for those whose disease has not been controlled by standard treatments.
This trial tests a new treatment called Descartes-08 for people with dermatomyositis or antisynthetase syndrome whose disease hasn't responded well to standard therapies. It aims to see if this treatment can help control muscle and skin symptoms.
This trial tests a special type of therapy called CAR-T cells, which are made from the patient's own blood cells and are designed to help control severe autoimmune diseases that haven't improved with other treatments. It is for children and young adults aged 5 to 19 with certain conditions like lupus, scleroderma, or myositis.
Hear when a new Juvenile Dermatomyositis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.