Clinical trials
Aged 65 Years or Older clinical trials
Below are recruiting aged 65 years or older clinical trials, each written for real people, not researchers. We’re tracking 1,068 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06192407Recruiting
Healthy fats and brain function in older adults
This study tests whether healthy fats (fatty acids) can support brain function as we age. If you are 65–75 and in good general health, you may be able to help researchers learn more about diet and the aging brain.
Burlington, VermontAges 65–75 - NCT06367738RecruitingPhase 1
Psilocybin and brain changes in healthy older adults
This study looks at how a single dose of psilocybin (the active ingredient in magic mushrooms) affects brain structure in healthy older adults. You'll receive the drug in a safe setting and have brain scans before and after to see if it promotes positive changes.
Berkeley, CaliforniaAges 60–85 - NCT06246929Recruiting
Healthy aging for Black adults with chronic pain and memory concerns
This study tests a program to help Black adults aged 50+ manage chronic pain and early memory changes. It compares two approaches to see which works better for improving daily life and thinking skills.
Boston, MassachusettsAges 50 years+ - NCT06107842Recruiting
Exercise program for older veterans' memory and thinking
This study tests whether an exercise program called Gerofit can help improve memory and thinking in older Veterans. If you join, you will take part in supervised exercise sessions to see how it affects your brain health.
West Los Angeles, CaliforniaAges 65 years+ - NCT06079398RecruitingPhase 2
Weekly injection for infants with achondroplasia
This trial tests a new weekly injection called TransCon CNP for infants with achondroplasia (the most common form of dwarfism). The goal is to see if it can help children grow better than a placebo (a shot with no medicine).
Saint Paul, MinnesotaAges birth–2 years - NCT06052826RecruitingPhase 2
Geriatric support to speed recovery after CAR-T for older adults
This study tests whether extra geriatric support before and after CAR-T cell therapy helps people 60 and older recover faster. It is for patients with B-cell non-Hodgkin lymphoma or multiple myeloma who are scheduled for an FDA-approved CAR-T treatment.
Duarte, CaliforniaAges 60 years+ - NCT03770312RecruitingPhase 4
Testing low/moderate statin use to prevent heart problems in older adults
This study looks at whether taking a low- to moderate-dose statin can prevent first-time heart and stroke problems in people age 70 and older. It may help you lower “bad cholesterol” (LDL) and see if that leads to fewer heart events over time.
SeoulAges 70 years+ - NCT06027554RecruitingPhase 2
MitoQ for frailty, walking, memory, and blood flow in older adults
This trial tests whether a supplement called MitoQ can improve blood vessel health, walking speed, and thinking skills in older adults who are frail or have mild memory problems. It aims to see if MitoQ helps maintain independence and quality of life.
Farmington, ConnecticutAges 65–80 - NCT06029933Recruiting
Comparing two flu vaccines for older adults
This study compares two types of flu shots for people 65 and older to see which works better. If you are a Kaiser Permanente member and get your flu shot at a Kaiser facility, this trial looks at your health records to see how well the vaccine protected you.
Oakland, CaliforniaAges 65 years+ - NCT05790720Recruiting
Propofol dosing study for older adults
This study looks at how the anesthetic drug propofol works in older adults during planned surgeries. The goal is to find the right dose for safe and effective anesthesia.
Santiago, Santiago MetropolitanAges 65–99 - NCT05766839RecruitingPhase 2
Potassium-lowering treatment for children under 12
This study tests a medicine called patiromer, which helps lower high potassium levels in the blood. It is for children under 12 who have high potassium that needs treatment for at least a month.
Aurora, ColoradoAges birth–11 years - NCT05752500Recruiting
Behavior coaching to help older adults with HIV move more
This study tests a tailored behavioral coaching program to increase physical activity in adults age 50+ who have HIV and are currently not very active. It may help you build safer, more routine movement using a Fitbit for tracking.
Minneapolis, MinnesotaAges 50 years+ - NCT05754151Recruiting
Mobile therapy for anxiety and depression in adults 40+
This trial tests whether a phone or tablet version of cognitive behavioral therapy (CBT) can help people ages 40 and older with anxiety or depression. It may help you manage symptoms with skills you can use between sessions.
New York, New YorkAges 40 years+ - NCT05725668Recruiting
Dual-task exercise to help prevent falls in memory trouble
This study tests a type of exercise training (doing a physical task while also doing a thinking task) to help older adults with mild memory problems prevent falls. If you have fallen before or have trouble with balance, this program may help you improve safety and coordination.
Springfield, OregonAges 65–95 - NCT05556928Recruiting
Cancer and aging study for adults with blood cancers
This study builds a registry to learn how aging and “resilience” relate to outcomes in people with blood cancers. You may be asked to complete questionnaires during UAB visits, which can help researchers better understand needs in older adults.
Birmingham, AlabamaAges 50 years+ - NCT05660980RecruitingPhase 1/Phase 2
Oral and monthly shots for HIV control in children
This trial studies whether a child can safely move from HIV medicine taken by mouth to long-acting monthly injections. It looks at keeping HIV levels suppressed (very low) and monitoring side effects and safety over time.
Atlanta, GeorgiaAges 2–11 - NCT05554692Enrolling by invitation
Study how aging and cochlear implants affect speech timing
This study looks at how the brain processes the timing of sounds and speech in people with cochlear implants and in people with typical hearing. It may help researchers understand what changes with age and how implant hearing works in the real world.
College Park, MarylandAges 18–85 - NCT05373940Recruiting
ICD placement to prevent sudden heart death in people over 70
This study looks at placing an ICD, a device that can stop dangerous heart rhythms, to help prevent sudden cardiac death. It is for people over 70 with specific heart function and heart failure symptoms.
Aix-en-ProvenceAges 70 years+ - NCT05266976Recruiting
Exercise types and bone markers in healthy older veterans
This study compares different ways of exercising to see how they affect “bone-related” blood markers in older adults. It may help you and researchers understand which exercise patterns support healthy bones.
Aurora, ColoradoAges 60 years+ - NCT05307666Enrolling by invitationPhase 4
Older adults using many medications may get simpler care
This study looks at whether older adults do better when their medication plan is simplified. You may be able to join if you’re at least 80, live in the community, and take 6 or more regular oral medications.
Edmonton, AlbertaAges 80 years+ - NCT05237687RecruitingPhase 2
Sirolimus to help prevent loss of daily function
This Phase 2 trial studies whether sirolimus can slow or prevent functional decline (more difficulty with daily activities) in older adults. You may be considered if you’re in the right age range and have no major heart, lung, liver, kidney, or recent bleeding/clotting problems.
Dallas, TexasAges 65–80 - NCT05183230Recruiting
Mobile program to help prevent suicide after hospital stay
This trial tests a phone-based (mobile) support program for middle-aged and older adults after a recent hospital stay for suicidal thoughts or an attempt. The goal is to reduce the chance of another suicidal crisis by providing structured support after discharge.
New York, New YorkAges 50–90 - NCT05124132Enrolling by invitation
Study of resilience and brain health after an earlier parent study
This trial looks at how resilience (how well people cope with stress) and brain health change over time in older adults who already joined an earlier study. You may be eligible if you participated in that “parent study.”
St Louis, MissouriAges 65 years+ - NCT04898790Recruiting
Testing ways to improve thinking after bone marrow transplant
This study looks at whether a physical activity program and related study measures can improve thinking and memory in older adults around the time of a stem cell transplant. If you qualify and participate, the team will compare outcomes between groups to see what approach works best.
Omaha, NebraskaAges 19 years+
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Common questions
- Are there clinical trials for aged 65 years or older?
- Yes. Clin2 currently lists 1,068 recruiting aged 65 years or older studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aged 65 years or older trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aged 65 years or older trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.