Clinical trials
Anal Fistula clinical trials
Below are recruiting anal fistula clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07520500Recruiting
Comparing two surgical techniques for high anal fistula
This trial compares two surgical methods (IFOC and LIFT) for treating high anal fistulas—abnormal tunnels that form near the anus. The goal is to determine which approach works better and has fewer side effects.
Cairo, Al-Manial, Cairo, EgyptAges 18 years+ - NCT04190862RecruitingPhase 1
Cell therapy for simple anal fistulas
This Phase 1 study tests whether a donated-cell treatment (given with a minor procedure) can help heal simple anal fistulas. It mainly focuses on safety first, but may also look at how well the fistula closes.
New York, New YorkAges 18 years+ - NCT05641844Recruiting
Minimally invasive treatment for anal fistulas with a seton
This trial tests whether RD2 Ver.02 is safe and works better than a comparison treatment for treating anal fistulas using a less invasive approach. It may help people who have a seton in place and want to avoid major surgery like flap repair or LIFT.
Los Angeles, CaliforniaAges 18 years+ - NCT06303752RecruitingPhase 1/Phase 2
Tissue therapy for complex anal fistula
This trial tests whether a special tissue therapy can help heal complex anal fistulas that involve a large part of the sphincter muscle. It is for adults who need surgery for this condition and do not have certain other health issues.
OdenseAges 18 years+ - NCT07477496Recruiting
Anal fistula surgery recovery study
This study follows people having surgery for an anal fistula to see how well they recover. It uses your feedback to measure results, and you'll have check-ins for a year.
AthensAges 18 years+ - NCT06113068Recruiting
Fistura procedure for complex anal fistulas
This trial tests a new procedure called Fistura to treat complex anal fistulas (abnormal tunnels between the anal canal and skin). It uses radiofrequency energy to close the fistula while preserving muscle. The study is for people whose fistula has already been drained with a temporary seton stitch.
Braine-l'AlleudAges 18 years+ - NCT07334678Recruiting
Two surgeries for high anal fistula: which works better?
This study compares two surgical techniques—TROPIS and coring-out fistulectomy—for treating high anal fistulas (a tunnel connecting the anal canal to the skin that goes through a lot of muscle). It aims to find which method helps heal better and is safer for you.
Cairo, Al-Manial CairoAges 18 years+ - NCT07081373Recruiting
Repeat dose of liposomal bupivacaine for pain after anal fistula surgery
This trial tests if a repeat dose of liposomal bupivacaine (a long-acting numbing medicine) helps reduce pain after surgery for anal fistula. It may be a good option if you are having this surgery and want better pain control.
Guangzhou, GuangdongAges 18–60 - NCT07128953Enrolling by invitationEarly Phase 1
Zuoqing San for anal fistula wound healing
This study tests if a traditional Chinese medicine called Zuoqing San can help heal the wound after anal fistula surgery better by reducing certain inflammatory processes. It may be an option for people who have had surgery for a simple anal fistula and whose wound is a specific size.
Hefei, AnhuiAges 18 years+ - NCT06798155Recruiting
Music to prevent pain after anal surgery
This study tests whether listening to a specific set of music before and after surgery for hemorrhoids, fistula, or anal fissure can help reduce pain. You would use a phone or tablet app to listen to short music sessions.
Saint-DenisAges 18 years+ - NCT06902987RecruitingPhase 1
Upatinib for anal fistulas in Crohn's disease
This trial tests whether upatinib can help heal active anal fistulas in people with moderate to severe Crohn's disease. If you have an anal fistula that is causing pain or drainage, this study may offer a new treatment option.
Guangzhou, GuangdongAges 18–70 - NCT05974280Recruiting
Stem cell treatment for complex anal fistulas
This trial compares two types of stem cell treatments to help heal complex anal fistulas (abnormal tunnels near the anus). You may be eligible if your Crohn’s-related disease is mostly controlled and the fistula has not fully healed with standard treatments.
Nantes, NantesAges 18 years+ - NCT06548724Recruiting
Quality of life after anal fistula surgery
This study looks at how fistula surgery affects your daily life and functioning. It may be a good option if you have an anal fistula that needs treatment.
Al Mansurah, DakahlyiaAges 18–80 - NCT06803550Recruiting
Recovery program after anal surgery
This trial tests a special recovery program after surgery for common non-cancerous anal conditions like hemorrhoids, anal fissures, or fistulas. The goal is to see if this approach helps you heal faster and feel better.
Al MansurahAges 18–65 - NCT07113795Enrolling by invitationEarly Phase 1
Chinese medicine and stem cells for Crohn's fistula
This trial tests a new approach that combines traditional Chinese medicine with stem cells to treat complex anal fistulas caused by Crohn's disease. It may help people whose Crohn's is not very active and who have not had major fistula surgery before.
Nanjing, JiangsuAges 18–60 - NCT07519850Recruiting
How Perianal Disease Affects Sexual Health and Quality of Life
This study explores how chronic perianal conditions—like anal fistulas or pilonidal disease—affect patients' sexual function and relationships. Researchers will ask you to complete surveys about your symptoms and sexual health to better understand this impact and help future patients.
Thessaloniki, ThessalonikiAges 18 years+ - NCT07021742Recruiting
BioHealx device study for anal fistula treatment
This study tests a device called BioHealx for closing anal fistulas that have not healed after previous treatment. It aims to see how well the device works in real-world use.
Fort Myers, FloridaAges 18–75 - NCT05243966Recruiting
Registry for soft tissue repair using a special matrix
This study is a registry that collects information from people who had soft tissue repair using a specific matrix and/or morcell material. It may help researchers understand how this approach performs in real-world care and patient outcomes over time.
Phoenix, ArizonaAges 18 years+ - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT02306382Recruiting
Study for diagnosing and treating perianal abscesses with surgery
This study focuses on people 18 and older who have a perianal abscess that needs surgical treatment. It aims to improve how these abscesses are diagnosed and managed, including care around surgery.
Umeå, County of Vasterbotten §Ages 18 years+
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Anal Fistula trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for anal fistula?
- Yes. Clin2 currently lists 20 recruiting anal fistula studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anal fistula trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anal fistula trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.