Clinical trials
Chronic Anal Fissure clinical trials
Below are recruiting chronic anal fissure clinical trials, each written for real people, not researchers. We’re tracking 8 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07665528Recruiting
Botox vs Botox with surgery for chronic anal fissure
This trial compares two treatments for a long-lasting anal fissure: Botox injections alone versus Botox combined with a small surgery (fissurectomy and anoplasty). It aims to see which works better and may help patients who have not healed with standard care.
Islamabad, FederalAges 18–65 - NCT06456073RecruitingPhase 1
Cell therapy for chronic anal fissures
This trial tests a new treatment made from special cells (called E-CEL UVEC) for people with long-lasting anal fissures that haven't healed with standard treatments. The goal is to see if this cell-based therapy can reduce pain and help the fissure heal.
New York, New YorkAges 18 years+ - NCT03855046RecruitingPhase 4
Testing complex treatment for long-lasting anal fissures
This trial studies a “combined” treatment approach for people who have had an anal fissure (a small tear in the anal area) for a long time. It may help reduce pain and improve healing, but you must meet specific safety rules to join.
Podolsk, Moscow OblastAges 18–70 - NCT04153032RecruitingPhase 2
Two ointments for painful recent anal fissures
This Phase 2 trial compares MEBO ointment with diltiazem ointment to see which one heals an acute anal fissure (a small tear causing pain). You may be able to join if your fissure is recent and very painful, and you can pause other anal-area ointments during the study.
BeirutAges 18 years+ - NCT06803550Recruiting
Recovery program after anal surgery
This trial tests a special recovery program after surgery for common non-cancerous anal conditions like hemorrhoids, anal fissures, or fistulas. The goal is to see if this approach helps you heal faster and feel better.
Al MansurahAges 18–65 - NCT07268261Recruiting
New surgery for chronic anal fissure
This trial tests a new combined surgical method for people with a chronic anal fissure (a small tear in the skin around the anus) that has not healed and is causing muscle spasms. The goal is to see if this surgery can help the fissure heal and relieve pain and spasm.
MoscowAges 18–70 - NCT07520552Recruiting
Comparing surgical techniques for chronic anal fissures
This study compares two surgical approaches to treat chronic anal fissures (painful tears in the anus) that haven't healed with conservative treatment. The goal is to determine which technique is safer and more effective.
Çanakkale, ÇanakkaleAges 18 years+ - NCT07519850Recruiting
How Perianal Disease Affects Sexual Health and Quality of Life
This study explores how chronic perianal conditions—like anal fistulas or pilonidal disease—affect patients' sexual function and relationships. Researchers will ask you to complete surveys about your symptoms and sexual health to better understand this impact and help future patients.
Thessaloniki, ThessalonikiAges 18 years+
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Common questions
- Are there clinical trials for chronic anal fissure?
- Yes. Clin2 currently lists 8 recruiting chronic anal fissure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic anal fissure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic anal fissure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.