Clinical trials · Pennsylvania
Bipolar Disorder clinical trials in Pennsylvania
We’re tracking 13 recruiting bipolar disorder studies with a site in Pennsylvania — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT05427123Recruiting
Study for kids and teens with bipolar or cyclothymic disorder
This trial is testing treatments for children and teens (ages 9–19) who have been diagnosed with bipolar disorder or cyclothymic disorder. It also requires regular participation from a caregiver so the team can track symptoms and response over time.
Pittsburgh, PennsylvaniaAges 9–19 - NCT06274567Recruiting
Brain stimulation for emotion in bipolar depression
This study tests a safe, non-invasive brain stimulation technique called iTBS to see if it can help people with bipolar disorder better manage their emotions during a depressive episode. It may offer a new option for those who are still feeling depressed despite stable medication.
Philadelphia, PennsylvaniaAges 24–65 - NCT06920940Recruiting
Ketogenic diet for bipolar disorder in teens
This study tests whether a ketogenic diet (a very low-carb, high-fat diet) can help teens with bipolar disorder who are currently feeling depressed or have mixed symptoms. Participants will receive medical and dietitian support while trying the diet for up to 12 weeks.
Pittsburgh, PennsylvaniaAges 12–21 - NCT07172516RecruitingPhase 3
Study of azetukalner vs placebo for bipolar depression
This trial tests whether the study drug azetukalner can help reduce depression symptoms in people with bipolar I or II disorder who are currently having a depressive episode. You would be randomly assigned to receive either the drug or a placebo (inactive pill) to see which works better.
Allentown, PennsylvaniaAges 18–74 - NCT07286175RecruitingPhase 2
Study of brenipatide for bipolar disorder
This trial tests an experimental drug called brenipatide for people with bipolar I or II disorder. It aims to see if the drug can help manage mood episodes when added to your current stable medications.
Philadelphia, PennsylvaniaAges 18–75 - NCT07217860Enrolling by invitationPhase 3
Long-term safety study of azetukalner for bipolar depression
This study is looking at the long-term safety of azetukalner for people with bipolar I or II depression who have already completed a previous trial of this drug. It is an open-label study, meaning everyone will receive the active medication.
Allentown, PennsylvaniaAges 18–75 - NCT06081426Recruiting
Ketogenic diet for bipolar disorder brain study
This study looks at how a ketogenic diet (very low carb, high fat) might affect brain function in people with bipolar disorder. Participants will follow the diet and have brain scans and blood tests to see how it helps mood and energy levels.
Pittsburgh, PennsylvaniaAges 18–40 - NCT07130500Enrolling by invitation
Rewards for sticking with long-acting injections
This study tests whether offering small rewards (like gift cards) can help people stick with a long-acting injection of their medication. It's for people with serious mental health conditions who have had a recent hospital stay or are at high risk of one.
Pittsburgh, PennsylvaniaAges 18–65 - NCT07389473Recruiting
Studying eye movements in long-term psychiatric medication use (Gaize device)
This trial uses a special device (Gaize) to track how your eyes move while you take psychiatric medication. It aims to see how long-term medication affects eye patterns, which could help doctors better understand treatment responses.
Philadelphia, PennsylvaniaAges 18–65 - NCT07220460RecruitingPhase 2
Study of an oral drug for bipolar depression
This trial tests an experimental pill (ABB-932) for people with bipolar I or II disorder who are currently in a depressive episode. The goal is to see if the drug is safe and helps improve mood.
Allentown, PennsylvaniaAges 18–65 - NCT06700902Recruiting
Support program for college students with mental health challenges
This study tests a program called 'Taking Action' to help college students with serious mental illnesses manage their health and daily life. If you're a student with a mental health condition, you may be able to join to learn new coping skills through group education.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05157620Recruiting
Yoga and exercise program for veterans with severe mental illness
This trial tests an exercise and yoga-style wellness program to help veterans with severe mental health conditions feel and function better. It may help with symptoms and overall well-being, especially if your condition is currently stable.
Pittsburgh, PennsylvaniaAges 18–70 - NCT07494305RecruitingPhase 2
Testing a new drug for bipolar depression
This trial tests an investigational drug called LB-102 for people with bipolar I disorder who are currently experiencing a major depressive episode without psychosis. It aims to see if the drug is safe and effective for treating depression symptoms.
Philadelphia, PennsylvaniaAges 18–65
Bipolar Disorder trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting bipolar disorder studies listed above.
- Lehigh Center for Clinical Research · 3 studies
- University of Pennsylvania · 2 studies
- University of Pittsburgh · 2 studies
- Adams Clinical
- Gaize
- Pittsburgh Mercy
- Temple University Hospital
- University of Pittsburgh Medical Center
What taking part in a bipolar disorder study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Bipolar Disorder trials in other states
Common questions
- Are there bipolar disorder clinical trials in Pennsylvania?
- Yes. We're currently tracking 13 recruiting bipolar disorder studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a bipolar disorder study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a bipolar disorder trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New bipolar disorder studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.