Clinical trials
Burden clinical trials
Below are recruiting burden clinical trials, each written for real people, not researchers. We’re tracking 169 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07708870Recruiting
Nurse-led support for older adults with advanced lung cancer
This study tests a nurse-led support program for older adults (65+) with advanced lung cancer and their main family caregiver. The goal is to see if special help from a nurse can improve quality of life for both you and your caregiver.
Taipei, TaipeiAges 18 years+ - NCT03549858Recruiting
Survey study on burdens and experiences of people with hemophilia
This study collects information from people with hemophilia about how treatments and daily life affect them. It uses your answers to improve patient-focused care and understand what challenges matter most.
Hamilton, OntarioAges Any age - NCT03638505Recruiting
Quality of life study for people with PSP and their caregivers
This study looks at quality of life for people with progressive supranuclear palsy (PSP) and the day-to-day burden on the caregiver. It may help researchers understand what support needs are most important and how caregiving affects wellbeing.
Marseille, PACAAges 18 years+ - NCT04212494Recruiting
Aspirating clot during heart procedure for certain heart attacks
This trial studies whether removing (“aspirating”) a blood clot during an emergency heart procedure works better for people having a specific type of heart attack with a large clot burden. It may help improve blood flow after treatment, but it is only for patients who meet several timing and safety conditions.
Fuzhou, FujianAges 18 years+ - NCT04251078Recruiting
Blood tests to track mutations in lower-risk MDS
This study uses repeated blood samples to watch how genetic changes in your blood evolve in lower-risk myelodysplastic syndrome (MDS). It may help doctors understand what mutation changes mean over time for people not on strong cancer-fighting treatments.
Badalona, BarcelonaAges 18 years+ - NCT04342234Recruiting
Neural network tool to measure cleft palate from scans
This trial studies a computer “neural network” that uses existing dental impressions, scans, and photos to measure cleft palate features. The goal is to reduce the amount of repeated cleft lip and palate clinic work for patients and families.
BaselAges Any age - NCT04556188Recruiting
Study to improve cardiac surgery services for rheumatic heart disease
This study looks at whether building a better, sustainable cardiac surgery service can reduce the burden of rheumatic heart disease. It focuses on patients who need cardiac surgery at a specific hospital during a training and research program.
Addis AbabaAges 14 years+ - NCT04743609Recruiting
Studying RSV illness impact in babies with ear or lung symptoms
This study looks at how RSV (a common virus that can affect breathing) leads to illness in young children who come to the doctor with ear infections and/or breathing symptoms. It may help doctors better understand the “burden” RSV causes in both home/outpatient and hospital settings.
CréteilAges 1 day–2 years - NCT05040555Recruiting
Testing a new chemo plan for newly diagnosed high-burden lymphoma
This trial studies a specific treatment plan to see how well it works for adults with newly diagnosed non-Hodgkin lymphoma that has a high amount of disease. It may help by aiming to control lymphoma more effectively, especially when it is widespread.
Changchun, JilinAges 18–75 - NCT05086692RecruitingPhase 1/Phase 2
Beta-only IL-2 therapy for advanced solid tumors
This Phase 1/2 study tests a beta-only version of IL-2, an immune-stimulating treatment, to shrink or control advanced or metastatic solid tumors. It’s mainly designed to check safety and to see if it can help patients by improving tumor response.
San Diego, CaliforniaAges 18 years+ - NCT05454969Recruiting
One-4-ALL initiative for patients, families, and care teams
This initiative includes both patient guardians and the healthcare providers who care for them. It likely tests or improves how care teams and families work together to support patients better.
Aurora, ColoradoAges 18–99 - NCT05496673Recruiting
Testing and preventing meningitis in rural Northern Uganda
This study helps doctors find meningitis (and rule it out) and improve screening and prevention in rural clinics. You might be included if you come to the clinic with symptoms that could be meningitis, or if you have HIV and are receiving care there.
LiraAges Any age - NCT05543681RecruitingPhase 2
Study drug for agitation in Alzheimer’s dementia with caregiver support
This Phase 2 trial tests a study medicine to reduce “agitation” behaviors in people with Alzheimer’s dementia. You and your caregiver would complete required assessments and may need genetic and blood testing to check how the body handles the drug.
Maitland, FloridaAges 60 years+ - NCT05632757Recruiting
Studying support for ALS patients and their family caregivers
This study looks at how much burden (stress and day-to-day strain) ALS creates for both the patient and the main caregiver. It may help shape better ways to support families facing ALS over time.
MarseilleAges 18 years+ - NCT05681858Recruiting
Testing heart inflammation and reduced blood flow in MINOCA
This study looks at why some people have chest pain and heart injury signs, but their heart arteries are not blocked. It tests scans of blood flow and heart tissue to better understand the cause and guide care.
BergenAges 18 years+ - NCT05733520Recruiting
Telehealth coaching for Alzheimer’s caregivers using a phone
This trial tests a mobile telehealth program designed to help unpaid caregivers reduce Alzheimer’s-related symptoms in the people they care for. If you’re a primary caregiver, you may get study sessions using a smartphone or similar device.
Indianapolis, IndianaAges 18 years+ - NCT05770102RecruitingPhase 2/Phase 3
Atezolizumab for cancers with high mutation or immune markers
This trial tests atezolizumab, a cancer immunotherapy, for people whose tumors have high mutation levels (TMB), or are “MSI-high,” or have CMMRD. It may help shrink cancer or slow its growth by boosting the immune system’s ability to recognize the tumor.
BelfastAges Any age - NCT05791305Recruiting
Testing programs to improve childhood nutrition
This study looks at how a nutrition and care program affects children under age 5 who attend it. It aims to help reduce the “double burden” of malnutrition—problems that can happen when children have both undernutrition and excess weight or related nutrition issues.
Addis Ababa, AmharaAges 2–5 - NCT05794386Recruiting
Ablation plan guided by left-heart scar map for persistent atrial fibrillation
This study tests whether using a 3D heart “scar map” helps doctors choose a better catheter ablation strategy for people with persistent atrial fibrillation (AF). It may help reduce ongoing AF by targeting the scar area in the left atrium.
Seoul, Jongno-guAges 19 years+ - NCT05811936Recruiting
SNAP support tool for head and neck cancer survivors and caregivers
This trial tests a “SNAP” support tool designed for people who have head and neck cancer and the caregiver who helps them. It aims to improve support and coping during and after cancer treatment by involving both the survivor and their main support person.
Charleston, South CarolinaAges 18 years+ - NCT05822193Recruiting
Study of long COVID in Brazil
This study looks at how often “post-COVID-19 condition” (long COVID) happens, what factors are linked to it, and how much it affects people’s daily lives. It may help researchers better understand long COVID and who is most impacted.
Cachoeirinha, Rio Grande do SulAges 18 years+ - NCT05852509Recruiting
Digital exercise program for heart failure family caregivers
This study tests a digital (phone-based) exercise program for older people who care for someone with heart failure. It may help you increase safe physical activity while also supporting the caregiver role.
Aurora, ColoradoAges 50 years+ - NCT05867706Recruiting
Study of caregiver stress after a loved one is near end of life
This study looks at how stress and grief affect caregivers of people with a terminal illness. It may help researchers understand what support or changes could help caregivers cope during the last months of life.
Zurich, Canton of ZurichAges 18 years+ - NCT05883540RecruitingPhase 2
LSD therapy in palliative care for comfort and well-being
This Phase 2 study tests how LSD may affect comfort and quality of life for people with advanced or end-stage life-limiting illness. It also checks whether the medicine is safe and can be given in a controlled way in palliative care settings.
BaselAges 22 years+
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Common questions
- Are there clinical trials for burden?
- Yes. Clin2 currently lists 169 recruiting burden studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a burden trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a burden trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.