Clinical trials
Cardiac clinical trials
Below are recruiting cardiac clinical trials, each written for real people, not researchers. We’re tracking 1,291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04077762Recruiting
Radial vs femoral access to reduce bleeding in heart procedures
This study compares two ways doctors can reach the heart during a catheter procedure: through the wrist (radial) or the groin (femoral). It aims to reduce bleeding and access-site complications, especially when patients may need a balloon/stent (PCI).
San Francisco, CaliforniaAges 18 years+ - NCT03934905RecruitingPhase 1/Phase 2
Sulforaphane supplement to protect the heart during doxorubicin
This trial tests whether a nutritional supplement called sulforaphane (SFN) can help protect heart function in people with breast cancer who are receiving doxorubicin (a chemotherapy that can affect the heart). Participants take caplets and have heart and safety monitoring to see if the supplement reduces heart-related side effects.
Lubbock, TexasAges 18–89 - NCT03546374Recruiting
Stop a common heart rhythm with surgery add-on therapy
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
Palo Alto, CaliforniaAges 18 years+ - NCT03303612Recruiting
Check monitoring vs guided pacing after valve replacement
This study compares two ways to decide when someone needs a pacemaker after they get a new heart valve (TAVI) and develop a new, persistent left bundle branch block (LBBB). It may help reduce unnecessary procedures while still keeping heart rhythms safe.
Edmonton, AlbertaAges 18 years+ - NCT03504956Recruiting
MRI study to map early heart artery plaque changes
This study uses an MRI scan to better “see and measure” early changes in the heart’s artery lining. It may help researchers understand coronary artery disease earlier, even before it causes symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT03446326Recruiting
Check how your pacemaker changes heart pumping
This study measures how well the heart pumps at different heart rates in people with pacemakers or defibrillators. It may help doctors understand how pacing settings affect heart function.
Calgary, AlbertaAges 18–70 - NCT03053141Recruiting
RHAPSODY mapping study during catheter procedures for heart rhythm
This study tests how heart electrical signals are mapped and recorded during a standard catheter procedure for atrial or ventricular rhythm problems. It may help researchers improve the way doctors analyze rhythm data, using a specific mapping system.
Birmingham, AlabamaAges 18 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT03292861Enrolling by invitationPhase 2
Thymoglobulin after first heart transplant: safety and effect
This trial tests whether Thymoglobulin® is safe and how well it works in people getting their first heart transplant. It may help doctors fine-tune medicines used to prevent the body from rejecting the new heart.
Los Angeles, CaliforniaAges 18–70 - NCT03253835Enrolling by invitation
MRI heart flow study to understand heart muscle damage
This study uses a special heart MRI to look at blood-flow patterns and how they relate to heart muscle injury. It may help researchers better understand different types of heart damage by comparing people with and without injury.
Graz, StyriaAges 20–80 - NCT02725060Enrolling by invitation
Study of autoimmune changes in postural tachycardia syndrome
This trial studies whether an autoimmune (immune system–related) process is involved in postural tachycardia syndrome (POTS), a condition where your heart rate rises when you stand. The study may help researchers understand what causes POTS and how it could be treated or monitored.
Oklahoma City, OklahomaAges 18–50 - NCT02573532Recruiting
Tracking heart damage after non-cardiac surgery
This study looks at whether patients experience heart muscle injury during or shortly after non-cardiac surgery. It aims to understand how common this is and what it means for recovery.
Basel, Canton of Basel-CityAges 45 years+ - NCT02670408Recruiting
Microarrays test in heart transplant care
This study checks how special lab tests on heart tissue samples can help guide diagnosis and treatment for people with a heart transplant. You may be eligible if you already need a heart tissue biopsy for a clinical reason and can provide consent.
Los Angeles, CaliforniaAges 18 years+ - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Birmingham, AlabamaAges Any age - NCT02013284Enrolling by invitation
Stool test to see if gut microbes predict heart risk
This study looks at your gut bacteria (from a stool sample) to see whether they can help predict heart risk in people being checked for blocked heart arteries. Your results may help researchers understand who is at higher risk and why.
Rochester, MinnesotaAges 18 years+ - NCT00271180Recruiting
Tracks long-term performance of Medtronic heart devices
This study follows how well certain Medtronic heart devices work over the long term. You may be included if you have a qualifying Medtronic implant and the research team can reliably get your implant and follow-up information.
Birmingham, AlabamaAges Any age - NCT00243776Recruiting
Study of heart tissue changes during certain heart surgeries
This study collects and analyzes small samples of heart tissue during specific heart operations in babies or children. The goal is to better understand how the heart develops after birth, which could improve future care.
Atlanta, GeorgiaAges Up to 20 years - NCT00181259Recruiting
MRI scan study of heart muscle chemistry
This trial uses a special MRI scan to look at how the heart muscle uses fuel. It may help researchers understand heart conditions like dilated cardiomyopathy and coronary artery disease, especially in people with reduced heart pumping.
Baltimore, MarylandAges 18 years+ - NCT01130545Recruiting
MRI testing of different scan methods in older adults
This study tests different MRI imaging techniques to improve how scans look and measure targets. You may be able to join with or without a contrast dye, and you’ll need to travel to the NIH for follow-up visits.
Bethesda, MarylandAges 18–100
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Common questions
- Are there clinical trials for cardiac?
- Yes. Clin2 currently lists 1,291 recruiting cardiac studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.