Clinical trials
Childhood clinical trials
Below are recruiting childhood clinical trials, each written for real people, not researchers. We’re tracking 421 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05286151Recruiting
Studying brain connectivity and timing in stuttering and nonstuttering teens
This study looks at how brain “networks” connect and how timing works in adolescents who stutter compared with those who don’t. It may help researchers better understand what underlies stuttering and how it differs from typical speech timing.
Ann Arbor, MichiganAges 9–13 - NCT05298995RecruitingPhase 1
GD2 CAR T-cell treatment for pediatric brain tumors
This trial tests a special immune-cell therapy (GD2 CAR T cells) made for pediatric brain tumor patients. It uses a planned treatment plan and monitoring to see if the therapy is safe and can work against the tumor.
Roma, ItalyAges 6 months–30 years - NCT05340348Recruiting
Study of a patient guide for young people at risk of psychosis
This study tests how a “patient guide” (Patientheque) may help young people who are either having a first psychosis episode or showing early warning signs. It aims to support care decisions and reduce stress by improving understanding and follow-up.
BrestAges 15–30 - NCT05375617Recruiting
Study for newly diagnosed childhood cancers in Europe
This study follows children and teens with newly diagnosed certain leukemia (ALL) and certain favorable brain tumors to learn best care and outcomes. It may help your team compare standard treatments and monitor health over time.
New York, New YorkAges 3–21 - NCT05427136Recruiting
Study early lung problems after childhood cancer treatment
This study looks for early lung (breathing) problems in children after certain cancer treatments, using lung tests and sometimes MRI scans. It may help doctors spot breathing complications earlier and guide better care.
BaselAges 4–22 - NCT05476770RecruitingPhase 1
Tagraxofusp for children with CD123-positive leukemia
This study tests tagraxofusp, a medicine that targets a marker called CD123 on cancer cells, in children and young adults whose leukemia or lymphoma has come back or is resistant to treatment. It may help by shrinking the cancer and improving disease control after standard therapies have not worked.
Los Angeles, CaliforniaAges 1–21 - NCT05481502Recruiting
Study looks at immune markers after cell therapy
This study collects immune and tumor-related samples to learn what predicts response to adoptive cell therapy (a treatment using immune cells). If you (or your child) are eligible, you may help researchers understand who benefits and why.
Villejuif, Val De MarneAges 2 years+ - NCT05483166Recruiting
Parent coaching to support memory and behavior after childhood cancer
This pilot study tests a program that works with parents to support a child’s thinking, memory, and behavior after childhood cancer treatment. It may help by teaching parents strategies to support school and day-to-day functioning.
AarhusAges 10–17 - NCT05504291RecruitingPhase 2
Treatment delivered inside the eye for retinoblastoma
This Phase 2 study tests a way to deliver cancer treatment directly inside the eye to treat retinoblastoma. It may help shrink the tumor while limiting treatment to the eye when possible.
Birmingham, AlabamaAges Up to 18 years - NCT05512169Recruiting
Genetic study in Indian children with newly diagnosed leukemia
This study looks at genetic (DNA) differences to understand acute lymphoblastic leukemia (ALL) in Indian children and how treatments may fit better. You may be able to join if your child is newly diagnosed, meets the study’s treatment plan rules, and provides consent.
New DelhiAges 1–18 - NCT05513833Recruiting
School hearing checks with remote specialty follow-up
This study offers hearing screening through schools in certain rural Kentucky counties and uses telemedicine (video/phone) to connect families with hearing specialists when needed. It may help by catching hearing problems earlier and speeding up referrals.
Lexington, KentuckyAges 3–11 - NCT05524610Recruiting
Screening plan for sexual health in young cancer survivors
This study tests a new way to screen for sexual problems in teens and young adults (ages 15–24) who have had childhood cancer. The goal is to better spot issues and improve care during survivorship.
Aurora, ColoradoAges 15–24 - NCT05593484Recruiting
School hearing screenings with telemedicine referral
This trial helps check children’s hearing at participating schools in rural Alaska, and then connects families with specialty care by video (telemedicine) if needed. It may help children get faster evaluation and support for hearing problems.
Anchorage, AlaskaAges 3–21 - NCT05668923Recruiting
Brain-scan study of speech patterns in people who stutter
This study uses MRI to look at brain signals involved in speech fluency. It may help researchers better understand what drives stuttering and how the brain supports fluent speech.
Ann Arbor, MichiganAges 5–17 - NCT05682131RecruitingPhase 4
Study for children with certain relapsed leukemia
This trial looks at treatment for children whose leukemia has come back for the first time. It focuses on a specific type of leukemia and risk level to see whether the approach improves outcomes.
Guangzhou, GuangdongAges 1–14 - NCT05747976Recruiting
Study for children with very high body size measurements
This study is building a program database for children who have unusually high body size measurements for their age. By collecting genetic and health information, researchers hope to better understand causes of obesity and guide care.
Houston, TexasAges Any age - NCT05754840RecruitingPhase 1/Phase 2
Cannabinoid treatment for children with hard-to-treat cancers
This early-phase study tests whether a cannabinoid medicine (including nabilone/cannabis-based treatment) can be given safely to children and teens with relapsed or refractory cancer. It may help with treatment options for children whose cancer has come back or did not respond to standard therapy.
Vancouver, British ColumbiaAges 4–18 - NCT05761197Recruiting
Study of mouth yeast infection and a preventive treatment
This trial studies children ages 9–15 months and looks at oropharyngeal yeast infection in the mouth (often called “OPC”). It may help researchers understand how to prevent or manage this condition.
Philadelphia, PennsylvaniaAges 9 months–1.3 years - NCT05783765Recruiting
Food, genetics, and behavior study for healthy children
This study looks at how eating, body factors (like weight), and behavior may relate to genetics in healthy children. Your child’s participation could help researchers understand why eating habits differ between families.
Philadelphia, PennsylvaniaAges 5–7 - NCT05786768RecruitingPhase 2/Phase 3
Obinutuzumab vs rituximab for relapsing childhood kidney syndrome
This study compares two antibody medicines, obinutuzumab and rituximab, to prevent relapses of steroid-dependent or frequently relapsing nephrotic syndrome in children. It looks at whether one option works better and is safer, including infection risk.
ParisAges 3–18 - NCT05792007Recruiting
Study of bone marrow environment in childhood leukemia
This study looks at what the bone marrow “microenvironment” is like in children newly diagnosed with acute leukemia, to better understand the disease. It also compares leukemia samples to samples from children having certain orthopedic surgery.
ToursAges 1–15 - NCT05798494Recruiting
Pre-pregnancy weight loss plan to protect child weight
This study tests whether a very low-calorie weight loss program before pregnancy can improve the chance that a child will have a healthier weight later. It follows families and stores samples from the child at home.
AarhusAges 18–38 - NCT05811845Recruiting
Testing blood monitoring of 6MP to help kids stay in remission
This trial is for children newly diagnosed with acute lymphoblastic leukemia (ALL). It tests whether checking medicine levels in the blood can help optimize ongoing treatment (maintenance) and potentially keep the cancer under control.
Monza, Monza BrianzaAges Up to 18 years - NCT05840575Recruiting
Study of thinking changes in young people during cancer treatment
This study looks at how thinking and memory may change in children and young adults after a new cancer diagnosis, especially around chemotherapy. It may help doctors better understand and track brain-related side effects early.
CopenhagenAges 7–29
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Common questions
- Are there clinical trials for childhood?
- Yes. Clin2 currently lists 421 recruiting childhood studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a childhood trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a childhood trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.