Clinical trials
Chronic Functional Constipation clinical trials
Below are recruiting chronic functional constipation clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07082673Recruiting
Sea buckthorn supplement for chronic constipation
This study tests a food supplement made from sea buckthorn to see if it helps people with chronic constipation have more regular and comfortable bowel movements.
NaplesAges 18–70 - NCT07387952Recruiting
Fecal transplant with nutrition help for chronic constipation
This trial tests if a fecal microbiota transplant combined with nutritional support can improve chronic constipation that hasn't gotten better with standard treatments. It's a small early study to see if the approach is safe and works.
BeijingAges 18–70 - NCT06526767Recruiting
Vibrating capsule for chronic constipation dose comparison
This study tests three different doses of a vibrating capsule (Vibrabot) to see which works best for relieving chronic constipation. If you have had constipation for at least 6 months and meet the Rome IV criteria, you may be able to join.
Beijing, Beijing MunicipalityAges 18–85 - NCT03819062Recruiting
Stomach–bowel nerve stimulation for long-term constipation
This trial studies a device that stimulates nerves near the lower back (sacrum) to improve bowel function in people with severe constipation that hasn’t responded to standard treatments. It may help if your constipation involves problems coordinating bowel movement and the muscles around the rectum.
Hamilton, OntarioAges 6–70 - NCT06543979RecruitingPhase 1/Phase 2
Anorectal manometry for children with chronic constipation
This study is for children aged 4–16 who have long-term constipation that doesn't get better with standard laxatives. It uses a test called anorectal manometry to measure how well the muscles in the bottom work, which can help guide treatment.
CairoAges 4–16 - NCT06221722Recruiting
Brain scan study for treating constipation
This trial uses brain scans to see if doctors can predict how well constipation treatments will work. It is for adults with functional constipation, but only if they have no other digestive problems or medical implants.
Yinchuan, NingxiaAges 18–45 - NCT06571097Recruiting
Levofloxacin for constipation from PIB bacteria
This study tests whether the antibiotic levofloxacin can help people with chronic constipation caused by a specific gut bacteria (PIB). If you have this bacteria and meet the other criteria, you may be able to join this trial to see if the treatment improves your symptoms.
Nanjing, JiangsuAges 18–70 - NCT07202481Recruiting
Fiber supplements for constipation in women
This trial tests if two types of fiber—one from chicory and one from a plant husk—can help women with constipation move food through their intestines faster. It aims to find a gentle, non-drug option that might work better than what you eat now.
Belo Horizonte, Minas GeraisAges 18–59 - NCT07261826Recruiting
Long-term effects of fecal microbiota transplant
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
Shanghai, Shanghai MunicipalityAges 3 years+ - NCT07382167RecruitingPhase 3
Study of Tenapanor for Chronic Constipation in Adults
This study tests an investigational drug called tenapanor for people with chronic idiopathic constipation (constipation with no clear cause). It aims to see if the drug can safely improve bowel movements in adults.
Foley, AlabamaAges 18–80 - NCT06911749Recruiting
Using MSOT and MRI to measure bowel transit in children
This trial tests whether two imaging techniques, MSOT and MRI, can safely and non-invasively measure how long it takes for food to move through the bowels in children with chronic constipation or other bowel emptying problems. It may help doctors better understand and treat these conditions.
Erlangen, BavariaAges 1 year+ - NCT07148583Recruiting
BioAmicus Complete for tummy troubles in babies
This study tests if a probiotic supplement called BioAmicus Complete can help babies with common digestive issues like colic, reflux, constipation, or loose stools. It might be a good option if your baby has these symptoms and you haven't used other probiotics or antibiotics recently.
Haiphong, Hai PhongAges birth–2 years - NCT06298331Recruiting
Aerobic exercise with abdominal massage for chronic constipation
This study tests whether adding aerobic exercise to abdominal massage helps people with chronic constipation. If you have ongoing constipation and haven't tried new treatments recently, you may be eligible.
AnkaraAges 18–65 - NCT04838522Recruiting
Prucalopride for constipation in breastfeeding women
This study looks at whether prucalopride (Motegrity/Resotran) can help constipation symptoms in women who are breastfeeding. It also monitors the breastfeeding infant during the study while you follow sample-collection and interview requirements.
La Jolla, CaliforniaAges 18 years+ - NCT06959758RecruitingPhase 4
Probiotics for childhood constipation
This study tests whether a probiotic supplement (BioKid LR) can help children with functional constipation — a condition where a child has hard, infrequent bowel movements with no other medical cause. The probiotic contains nine different types of good bacteria, including L. reuteri.
AfulaAges 6 months–17 years - NCT07135362Recruiting
Probiotic for improving constipation in adults
This trial tests a probiotic supplement to see if it helps improve bowel function in people with constipation. If you have functional constipation (not caused by another illness), this study may be a good fit.
TaipeiAges 18–65 - NCT04506593Recruiting
GI Motility diagnosis registry for people with digestion movement problems
This trial is a registry, meaning it collects information about people being evaluated for problems with how the gut moves. It may help doctors better diagnose gastrointestinal motility disorders in the future.
Indianapolis, IndianaAges Any age - NCT07323407Recruiting
Brain stimulation for hard-to-treat constipation with bodily distress
This trial tests if a gentle electrical current applied to the scalp can improve severe constipation in people who also experience persistent physical symptoms (like pain or bloating) that cause high worry. It is for those who have not gotten relief from standard laxatives.
Xi'an, ShaanxiAges 18–80 - NCT06106685RecruitingPhase 1/Phase 2
Washed microbiota transplant for chronic constipation
This trial tests a treatment called washed microbiota transplantation (a procedure that delivers healthy gut bacteria to your colon) for adults with chronic constipation. The goal is to see if it can improve bowel movements without the need for laxatives.
Nanjing, JiangsuAges 18–70 - NCT07065942Recruiting
Lactulose for gut health in diabetes with constipation
This study tests if a common stool softener called lactulose can improve gut health and metabolism in people with type 2 diabetes and long-term constipation. It aims to see if changing gut bacteria can help both digestion and blood sugar control.
BeijingAges 18–70 - NCT07213856Recruiting
Dietary help for constipation in Parkinson's disease
This study tests whether a special diet can help improve constipation symptoms in people with early-stage Parkinson's disease. It aims to see if changing what you eat can make bowel movements more regular and comfortable.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06847919Recruiting
Probiotic yogurt for chronic constipation
This study tests whether eating a special probiotic yogurt can help relieve chronic constipation. It may be a simple, natural addition to your diet with minimal side effects.
Suzhou, JiangsuAges 18–65 - NCT07126327Recruiting
Testing a new low-volume cleansing system for bowel issues
This study tests a new device called Peristeen Light, which is a low-volume system for cleaning the bowels. It may help people with constipation or stool leakage who need this kind of treatment every other day.
Aarhus, GotlandAges 18 years+ - NCT07388264Recruiting
Probiotic for bloating and gut health
This study tests a probiotic (a good bacteria) called Weizmannia coagulans to see if it helps reduce bloating and improves gut health. Researchers will check how your digestion changes by looking at your stool and gut bacteria.
Saint Charles, MissouriAges 18–50
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Common questions
- Are there clinical trials for chronic functional constipation?
- Yes. Clin2 currently lists 25 recruiting chronic functional constipation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic functional constipation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic functional constipation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.