Clinical trials
Constipation - Functional clinical trials
Below are recruiting constipation - functional clinical trials, each written for real people, not researchers. We’re tracking 154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07175922Recruiting
A study of gene changes in people with Parkinson's disease
This study looks at how the csgA gene changes over time in people with Parkinson's disease, especially if they have stomach or bowel issues. It aims to help understand how these changes might relate to symptoms.
LeidenAges 18–80 - NCT07722585RecruitingPhase 1
New tablet study: absorption and food effects
This study tests a new form of the drug nurandociguat tablet to see how well it is absorbed compared to the old tablet, and whether food changes how it works. Healthy volunteers are needed to take the tablets and have their blood levels checked.
BerlinAges 18–58 - NCT06888154Recruiting
Hot compress use after open abdominal surgery
This trial tests if applying a warm compress to the abdomen after open belly surgery can help recovery. It aims to see if this simple, drug-free method reduces pain or improves bowel function.
Merkez, KırşehirAges 18–65 - NCT07482696Recruiting
Biofeedback training for pelvic floor muscle issues in constipation
This trial tests whether electromyographic biofeedback therapy can help people who have trouble relaxing their pelvic floor muscles during bowel movements, a condition called dyssynergic defecation. It may improve chronic constipation and hard stools.
Kocaeli, IzmitAges 18–70 - NCT06578936Recruiting
Massage and warmth after knee replacement
This study tests whether gentle belly massage and a warm pack help people have a bowel movement more quickly after total knee replacement surgery done under spinal anesthesia. It looks at how these simple, drug-free treatments may help get your bowels working again after surgery.
AdanaAges 18 years+ - NCT07749092Recruiting
Kimchi powder for gut health in IBS
This study tests whether taking kimchi powder (a dried form of the fermented cabbage dish) can improve gut health and symptoms in people with diarrhea-predominant IBS. You'll avoid regular kimchi for about 2 months, then take the powder daily and track how you feel.
YangsanAges 20–70 - NCT04819217Recruiting
Probiotics and a toxin binder to slow chronic kidney disease
This trial studies an oral product (a “uremic toxin” absorber) plus probiotics to help slow the progression of chronic kidney disease. It may help by lowering harmful gut-related substances that can build up when kidney function is reduced.
TaipeiAges 20 years+ - NCT04623359Recruiting
Testing a detailed bowel pressure test for hard-to-treat constipation
This study checks whether a “high-resolution manometry” test (a thin tube measuring bowel muscle pressure) helps doctors understand and manage constipation. It’s for adults with long-lasting constipation that has not improved with standard laxatives, and who meet specific safety and colon-testing criteria.
CaenAges 18 years+ - NCT05796388Recruiting
Virtual reality and linaclotide for IBS with constipation
This study tests whether virtual reality (VR) plus linaclotide can improve symptoms and quality of life in adults with IBS-C (IBS with constipation). You may be asked to use VR and take a study medicine, while doctors check that your IBS diagnosis fits strict criteria.
Jacksonville, FloridaAges 18–70 - NCT06205862RecruitingPhase 2
Fecal transplant for preventing colon polyp return
This study tests whether taking capsules of healthy bacteria (fecal microbiota transplant) can help prevent colon polyps from coming back after they have been removed. It might be an option for people who have had an adenoma polyp removed and want to reduce the chance of recurrence.
Guangzhou, GuangdongAges 18–75 - NCT07032376Enrolling by invitation
Quick care pathway for chronic constipation
This study tests a faster care plan for people with chronic constipation. It will see if a simplified approach helps patients get the right treatment sooner.
Ann Arbor, MichiganAges 18 years+ - NCT07607249Enrolling by invitation
Floating Needle Treatment for Stomach Issues After Knee Surgery
This trial tests whether a traditional Chinese acupuncture technique called 'floating needle' can help with stomach and bowel problems that sometimes happen after knee surgery under general anesthesia. You would receive this treatment along with standard post-surgery care to see if it reduces nausea, constipation, or other digestive issues.
Guangzhou, GuangdongAges 18 years+ - NCT06506786Recruiting
Fresh fruits and vegetables and your gut health
This study looks at how eating fresh garden foods affects the bacteria living in your gut (your microbiome). If you qualify, you may be able to take part in a 3-month study this fall.
Eugene, OregonAges 18–45 - NCT05133024RecruitingPhase 2
Beetroot juice to help prevent bowel slowdown after colon surgery
This Phase 2 study tests whether drinking beetroot juice can reduce “postoperative ileus,” when the intestines temporarily don’t move normally after colorectal surgery. If it works, it may help you recover bowel function sooner after an elective laparoscopic colon and upper rectum operation.
EdegemAges 18 years+ - NCT07083596Recruiting
Fermented milk drink for constipation relief in Filipino adults
This study tests if a special fermented milk drink can help relieve constipation symptoms like hard or lumpy stools. Researchers want to see if it works for adults who have constipation without a known medical cause.
Manila, ManilaAges 18–59 - NCT06633250Recruiting
Testing a rice-based formula for babies with cow's milk allergy
This trial tests a special formula made from hydrolyzed rice protein in babies with cow's milk protein allergy. The goal is to see if the formula supports healthy growth and is well-tolerated, while also improving quality of life.
BerlinAges Up to 8 months - NCT04788914Recruiting
Test saliva or blood markers to track kidney and leg disease treatment
This study looks at a gene marker (“lncRNA,” a natural molecule in the body) to see how well an oral absorbent, with or without probiotics, is helping people with chronic kidney disease (CKD) who also have blocked leg arteries. It may help doctors better measure treatment impact and tailor care.
Taipei, TaiwanAges 20 years+ - NCT07229014Recruiting
Collagen supplement for quality of life and appetite
This trial tests whether a daily collagen supplement can improve quality of life, appetite, and blood sugar control in overweight adults who feel low energy or have trouble sleeping. You will take the supplement, use a continuous glucose monitor, and complete online surveys.
London, LondonAges 18–65 - NCT07425249Recruiting
Chewing gum after stomach or bowel surgery
This trial tests if chewing gum after open stomach or bowel surgery can help your intestines start moving again sooner. It is for people undergoing open gastrointestinal surgery who do not have certain health conditions or take specific medicines.
Peshawar, KPKAges 17–85 - NCT04113382RecruitingPhase 1/Phase 2
A bowel prep study for children having a colonoscopy
This trial tests a bowel-cleansing liquid called CLENPIQ in children ages 1 to 9 who need a colonoscopy. It aims to see if it works well and is safe for preparing the colon before the procedure.
Mobile, AlabamaAges 1–8 - NCT07420231Recruiting
Prebiotic and Postbiotic for Digestive Comfort
This trial tests whether taking a prebiotic and a postbiotic together can help reduce intestinal discomfort such as bloating, gas, or stomach pain. If you have ongoing mild to moderate digestive symptoms, this study may offer a new approach to feeling better.
Louvain-la-Neuve, Brabant WallonAges 18–75 - NCT06562907RecruitingPhase 1
Study of GS-4571 in healthy people, people with obesity, and people with type 2 diabetes
This trial tests an experimental drug called GS-4571 in three groups: healthy individuals, people with obesity (but not diabetes), and people with type 2 diabetes who are not obese. The study aims to see how the drug affects the body and how safe it is.
Miami, FloridaAges 18–55 - NCT07218523RecruitingPhase 3
Bowel cleansing study for children having a colonoscopy
This study tests a bowel-cleansing medicine called PLENVU against another medicine (sodium picosulfate) in children aged 1 to under 18 who need a colonoscopy. The goal is to see which one works better at cleaning the bowel before the procedure.
Edegem, AntwerpAges 1–17 - NCT06494917Recruiting
Manual therapy and pelvic floor exercises for constipation
This trial tests whether manual therapy (hands-on muscle work) and pelvic floor exercises can help people with constipation. It's a chance to try a non-medication approach for better bowel function.
ŞırnakAges 18–55
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Common questions
- Are there clinical trials for constipation - functional?
- Yes. Clin2 currently lists 154 recruiting constipation - functional studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a constipation - functional trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a constipation - functional trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.