Clinical trials · California
Cognitive Impairment clinical trials in California
We’re tracking 36 recruiting cognitive impairment studies with a site in California — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT05625425Recruiting
Study testing a memory and wayfinding training program
This study tests a wayfinding (getting around) training program and how it may affect long-term memory. You may need brain scans (fMRI), virtual reality tasks, and regular short walks to participate.
San Francisco, CaliforniaAges 60–85 - NCT05929703Recruiting
Care approach for hospitalized older adults at risk of confusion
This trial tests new ways to help hospitalized older adults (and their family/care partners) stay comfortable and avoid or reduce episodes of acute confusion. It focuses on people who are likely to develop delirium during their hospital stay.
Orange, CaliforniaAges 70 years+ - NCT05980117RecruitingPhase 4
Remimazolam sedation for cataract surgery
This study tests a sedative, remimazolam, for older adults having their first cataract surgery. It aims to see if it helps keep patients comfortable and calm without needing general anesthesia.
Los Angeles, CaliforniaAges 65 years+ - NCT06090578Recruiting
Brain health check for adults in primary care
This trial tests a new brain health assessment tool in primary care clinics. It may help your doctor better detect thinking or memory changes early.
Pasadena, CaliforniaAges 18 years+ - NCT06502964RecruitingPhase 2
ALTO-101 study for schizophrenia cognitive symptoms
This study tests an experimental medication called ALTO-101 for people with schizophrenia who also have cognitive impairment (memory or thinking problems). It aims to see if the drug can improve these symptoms while you continue your current antipsychotic treatment.
Walnut Creek, CaliforniaAges 21–55 - NCT06548191RecruitingPhase 1
Time-Restricted Eating for Alzheimer's Disease
This study tests whether a time-restricted eating schedule (eating all meals within a 10-hour window each day) can improve memory and thinking in people with early Alzheimer's disease or mild cognitive impairment. Healthy partners of people with memory problems can also join as a comparison group.
San Diego, CaliforniaAges 60 years+ - NCT06916221Recruiting
Digital brain training in aging
This study tests whether a digital intervention can help older adults (60+) maintain or improve cognitive function. It is designed for healthy adults or those with mild cognitive impairment (MCI), and people who do not regularly play a musical instrument or have extensive music training.
San Francisco, CaliforniaAges 60–85 - NCT06918704Recruiting
Digital brain health program for older adults
This study tests a digital program designed to help support thinking and memory in older adults. It may be a good fit if you are 60+ and generally healthy, even if you have some mild memory concerns.
San Francisco, CaliforniaAges 60–85 - NCT06976203RecruitingPhase 3
Testing karxt for thinking problems in alzheimer's
This trial tests if a combination medicine, KarXT plus KarX-EC, can help with thinking and memory problems in people with mild to moderate Alzheimer's disease. It aims to see if the treatment is safe and effective.
Fullerton, CaliforniaAges 60–85 - NCT07516119Recruiting
Predicting Alzheimer's Risk Before Memory Loss Occurs
This study identifies people at high risk for Alzheimer's disease before symptoms develop, using genetics and digital tools to track brain health over time. If you qualify, you'll help researchers understand who will develop cognitive decline and potentially enable earlier interventions.
San Diego, CaliforniaAges 55 years+ - NCT06023446Enrolling by invitation
Can eye photos detect early Alzheimer's disease?
This study uses a special camera (OCT) to take pictures of the retina (the back of your eye) to see if it can detect Alzheimer's disease very early. You may be eligible if you are either cognitively normal or have mild cognitive impairment, and have already had a test for Alzheimer's-related brain changes.
Sacramento, CaliforniaAges 50–89 - NCT05215886Enrolling by invitation
Bariatric surgery and memory problems in people with obesity
This study looks at how bariatric (weight-loss) surgery may affect memory and thinking in people with obesity who already have memory decline or dementia. It may help doctors understand which patients benefit most and what changes to expect.
Sacramento, CaliforniaAges 18–75
Cognitive Impairment trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting cognitive impairment studies listed above.
- University of California, San Francisco · 3 studies
- University of California, Davis Medical Center · 2 studies
- Foster Carr MD
- Fullerton Neurology and Headache Center
- Inglewood Clinical
- Kaiser Permanente Southern California
- Local Institution - 0069
- Research Site
What taking part in a cognitive impairment study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cognitive Impairment trials in other states
Common questions
- Are there cognitive impairment clinical trials in California?
- Yes. We're currently tracking 36 recruiting cognitive impairment studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cognitive impairment study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cognitive impairment studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.