Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 577 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07786116Recruiting
Gut bacteria in Parkinson's disease and related conditions
This study looks at how certain gut bacteria (methanogens) are involved in the progression of Parkinson's disease and related conditions. It aims to understand the connection between gut health and brain health, which may lead to better treatments.
Cambridge, CB2Ages 55 years+ - NCT07764250Recruiting
Comparing two balance training approaches for older adults with mild to moderate memory or thinking problems
This study compares two types of balance training (one where you stand still and one where you stand while doing a task) for older adults with mild to moderate thinking or memory problems. It aims to see which training is better for improving balance and daily function.
Islamabad, CapitalAges 55 years+ - NCT07775079Recruiting
Comparing exercise training approaches for older adults with mild memory problems
This study tests two different ways of combining physical and mental exercises to see which helps older adults with mild to moderate memory problems improve their thinking and daily function better.
Islamabad, IslamabadAges 4.6 years–7.1 years - NCT05014399Recruiting
Study memory changes during chemotherapy for colorectal cancer
This study looks at cognitive (thinking and memory) changes in people with colorectal cancer who start certain chemotherapy drugs. It aims to understand how treatment affects the brain and may guide better monitoring or support during care.
Fort Wayne, IndianaAges 18 years+ - NCT07760545Recruiting
Memory screening by video before surgery
This study tests whether doing a quick memory and thinking check over video call is as reliable as doing it in person. You would take part before your scheduled surgery to help improve how cognitive health is assessed.
Vancouver, British ColumbiaAges 65 years+ - NCT05201534Recruiting
Math and thinking skills training for school-age children
This trial studies interventions to improve math and cognitive (thinking) skills in elementary school children. It includes both children with math learning difficulties and typically developing children, using tests and MRI brain scans for those who can participate.
Palo Alto, CaliforniaAges 6–12 - NCT06444568Recruiting
Ketogenic diet for memory loss in older adults
This trial tests whether a modified ketogenic diet (high in healthy fats, low in carbs) can help people with mild memory problems. It is for older adults who have been diagnosed with a certain type of memory impairment and want to see if diet changes can support brain health.
AnkaraAges 65–80 - NCT07287527Recruiting
Light therapy for memory and brain health
This study tests whether a type of light therapy called photobiomodulation can improve brain connections and thinking abilities in people with mild memory problems.
IstanbulAges 55 years+ - NCT07735910Recruiting
Binaural beats for memory in older adults with mild cognitive impairment
This trial tests whether listening to special sounds called binaural beats can help older adults with mild memory or thinking problems improve their cognitive function. If you live in a nursing home and have mild cognitive impairment (not dementia), you may be able to join.
Shenyang, LiaoningAges 60 years+ - NCT07736885Recruiting
Hand stimulation for thinking problems after stroke
This study tests a gentle, painless electrical stimulation on specific points on the hands to see if it helps improve thinking and memory after a stroke. It is for people who have had a stroke in the last 2 weeks to 6 months and are noticing some cognitive changes.
Tianjin, Tianjin MunicipalityAges 35–80 - NCT07733726Enrolling by invitation
Dual-Task Mouth and Memory Training for Oral Frailty
This study tests a program that combines mouth exercises with memory tasks to see if it can improve both chewing, swallowing, and thinking skills in people who have oral frailty and some memory decline.
KowloonAges 50 years+ - NCT06601933RecruitingPhase 2
Computer thinking exercises for memory concerns in older adults
This study tests whether a computer-based thinking exercise program can improve memory and brain function in older adults with mild memory concerns. If you have age-related memory changes but not dementia, you may be able to join and get a free MRI scan.
Miami, FloridaAges 55–89 - NCT07731334Recruiting
Memory problems in non-neurology rehab patients
This study looks at how common mild cognitive impairment and dementia are in people staying in rehabilitation units for heart, lung, or orthopedic problems. It aims to understand memory and thinking issues that may be overlooked in these settings.
Florence, FIAges 45 years+ - NCT07243600Recruiting
Brain Training for Memory in Mild Cognitive Impairment
This study tests a computer-based brain-training program designed to improve memory and thinking skills in older adults with mild cognitive impairment (MCI). It aims to see if these exercises can help keep the brain healthy and slow down memory decline.
Montreal, QuebecAges 65 years+ - NCT07717567Recruiting
Blood tests to diagnose and predict Alzheimer's disease
This study is testing whether a simple blood test can help diagnose Alzheimer's disease and predict how the disease will progress. If you have memory or thinking problems that have been getting worse, you may be able to join.
Milan, MilanoAges 40 years+ - NCT03851523Recruiting
Tracking memory changes in people with early Alzheimer’s symptoms
This study follows people over time to better understand how memory and thinking complaints progress in early Alzheimer’s disease (from “subjective cognitive decline” to mild cognitive problems). It may help researchers understand who is likely to decline and how symptoms change, which could support future treatments.
Barcelona, CataloniaAges 45 years+ - NCT04356924Recruiting
Talking therapy to help with worries from mild memory problems
This trial studies a psychological (talking) treatment to help people cope with everyday life challenges caused by mild cognitive impairment or subjective cognitive decline. It may help reduce anxiety, avoidance, and feelings of stigma linked to memory or thinking changes.
Stockholm, Stockholm CountyAges 45–75 - NCT04817566Recruiting
Brain stimulation and training for thinking problems after breast cancer
This study tests whether brain stimulation plus cognitive training can improve thinking and memory problems in women after chemotherapy for breast cancer. It may help if you still feel “foggy” or have trouble concentrating months after treatment.
GreifswaldAges 18–65 - NCT05079464Recruiting
Exercise plus brain stimulation to improve memory in early impairment
This trial tests whether a supervised exercise program, paired with brain stimulation, can improve thinking and memory in people with early “vascular” cognitive problems (not dementia). It may help your brain function before memory loss becomes more severe.
Toronto, OntarioAges 50 years+ - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT05446584RecruitingPhase 2
Study memory changes in people with past mild head injury
This Phase 2 study looks at how memory problems (amnestic mild cognitive impairment) may relate to a history of a mild traumatic brain injury. It compares people with a past mild head injury to people without one to better understand what might be driving memory symptoms.
Dallas, TexasAges 55 years+ - NCT05495087Recruiting
Breathing low-oxygen air to test brain benefits in mild memory loss
This study tests whether breathing controlled low-oxygen air (through a disposable face mask) can improve brain function in people with mild cognitive impairment (MCI). You’d be randomly assigned to the real treatment or a sham (placebo-like) control, and you’d need multiple lab visits.
Fort Worth, TexasAges 55–79 - NCT05540613Recruiting
Tai Chi versus exercise to help thinking in mild memory loss
This study compares Tai Chi with conventional exercise to improve thinking and memory in older adults who have mild cognitive impairment. If you qualify, you may be asked to do a supervised exercise program and be tested on thinking abilities over time.
Hong KongAges 50 years+ - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80
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Cognitive Impairment trials by city
Studies with a site in or near these metro areas.
Cognitive Impairment trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 577 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.