Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 569 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06051240RecruitingPhase 2
Lithium to prevent thinking problems after brain radiation
This study tests if the drug lithium can help prevent memory and thinking problems that sometimes happen after brain radiation for a brain tumor. You may qualify if you are under 18 when treated and had radiation within the last 7 years.
Solna, Stockholm CountyAges 5 years+ - NCT06467253Recruiting
Brain stimulation plus memory training for mild memory loss
This study tests two gentle brain stimulation methods combined with memory training for people with mild memory loss. It aims to help improve thinking and memory skills over 8 weeks at a psychiatric hospital in Mexico City.
Mexico CityAges 55–85 - NCT07818369Recruiting
Gut bacteria and fiber supplement for mild memory problems
This study tests whether a daily supplement containing special bacteria and fiber from agave (a type of prebiotic) can improve memory and thinking in older adults with mild cognitive impairment. It looks at the connection between the gut and the brain.
Mexico City, Mexico CityAges 60–75 - NCT07786116Recruiting
Gut bacteria in Parkinson's disease and related conditions
This study looks at how certain gut bacteria (methanogens) are involved in the progression of Parkinson's disease and related conditions. It aims to understand the connection between gut health and brain health, which may lead to better treatments.
Cambridge, CB2Ages 55 years+ - NCT07775079Recruiting
Comparing exercise training approaches for older adults with mild memory problems
This study tests two different ways of combining physical and mental exercises to see which helps older adults with mild to moderate memory problems improve their thinking and daily function better.
Islamabad, IslamabadAges 4.6 years–7.1 years - NCT07764250Recruiting
Comparing two balance training approaches for older adults with mild to moderate memory or thinking problems
This study compares two types of balance training (one where you stand still and one where you stand while doing a task) for older adults with mild to moderate thinking or memory problems. It aims to see which training is better for improving balance and daily function.
Islamabad, CapitalAges 55 years+ - NCT07760545Recruiting
Memory screening by video before surgery
This study tests whether doing a quick memory and thinking check over video call is as reliable as doing it in person. You would take part before your scheduled surgery to help improve how cognitive health is assessed.
Vancouver, British ColumbiaAges 65 years+ - NCT06453746Recruiting
Non-drug program to prevent dementia for mild cognitive impairment
This study tests whether non-drug activities (like exercise, brain games, or lifestyle changes) can help prevent dementia in older adults with mild memory loss. You will take part in a program at the hospital and have regular checkups.
Ho Chi Minh CityAges 60 years+ - NCT07736885Recruiting
Hand stimulation for thinking problems after stroke
This study tests a gentle, painless electrical stimulation on specific points on the hands to see if it helps improve thinking and memory after a stroke. It is for people who have had a stroke in the last 2 weeks to 6 months and are noticing some cognitive changes.
Tianjin, Tianjin MunicipalityAges 35–80 - NCT07735910Recruiting
Binaural beats for memory in older adults with mild cognitive impairment
This trial tests whether listening to special sounds called binaural beats can help older adults with mild memory or thinking problems improve their cognitive function. If you live in a nursing home and have mild cognitive impairment (not dementia), you may be able to join.
Shenyang, LiaoningAges 60 years+ - NCT07733726Enrolling by invitation
Dual-Task Mouth and Memory Training for Oral Frailty
This study tests a program that combines mouth exercises with memory tasks to see if it can improve both chewing, swallowing, and thinking skills in people who have oral frailty and some memory decline.
KowloonAges 50 years+ - NCT07731334Recruiting
Memory problems in non-neurology rehab patients
This study looks at how common mild cognitive impairment and dementia are in people staying in rehabilitation units for heart, lung, or orthopedic problems. It aims to understand memory and thinking issues that may be overlooked in these settings.
Florence, FIAges 45 years+ - NCT07717567Recruiting
Blood tests to diagnose and predict Alzheimer's disease
This study is testing whether a simple blood test can help diagnose Alzheimer's disease and predict how the disease will progress. If you have memory or thinking problems that have been getting worse, you may be able to join.
Milan, MilanoAges 40 years+ - NCT07672938Recruiting
Olive supplement and Mediterranean diet for mild memory loss
This trial tests whether a dietary supplement made from olive polyphenols, combined with following a Mediterranean diet, can help protect thinking and memory in people with mild cognitive impairment (MCI). It may be a good fit if you have early memory changes and want to try a nutrition-based approach.
Thessaloniki, Central MacedoniaAges 50–85 - NCT07638748Recruiting
Virtual Reality Brain Training for Memory Loss
This study tests whether a virtual reality program that combines thinking exercises and movement can help people with early memory problems or cognitive concerns. Researchers want to see if it's easy to use, helpful, and something people would actually want to do.
Houston, TexasAges 55–90 - NCT07598409Recruiting
Brain Training Program for Older Adults in Spain
This study tests whether a computer-based brain training program can help older adults maintain or improve their thinking and memory skills. Researchers will compare people with normal thinking abilities to those with mild memory problems to see if the training helps both groups.
Madrid, MadridAges 65 years+ - NCT05540613Recruiting
Tai Chi versus exercise to help thinking in mild memory loss
This study compares Tai Chi with conventional exercise to improve thinking and memory in older adults who have mild cognitive impairment. If you qualify, you may be asked to do a supervised exercise program and be tested on thinking abilities over time.
Hong KongAges 50 years+ - NCT06058611Recruiting
Computer brain training vs. fun activities for memory
This study compares two types of brain activities: a computer-based cognitive training program and engaging leisure activities like puzzles or games. The goal is to see which approach better helps memory and thinking skills in older adults with mild cognitive concerns.
Zaragoza, ZaragozaAges 50 years+ - NCT07558785Enrolling by invitation
Testing speech and memory checks at home for early thinking problems
This study uses a video-based system at home to check your speech and memory, helping doctors spot thinking problems early using artificial intelligence. The goal is to see if this simple, at-home test can reliably catch early memory and thinking changes.
PilsenAges 40 years+ - NCT07517380Recruiting
Brain exercises and lifestyle program for mild memory loss
This study tests whether guided exercises targeting memory, thinking skills, and daily habits can help people with mild cognitive impairment (early memory or thinking problems that don't severely impact daily life). You'll participate in a structured rehabilitation program designed to support brain health.
Milan, MilanoAges 50 years+ - NCT07519798Enrolling by invitation
Brain Stimulation for Memory Problems in Older Adults
This study tests a new, non-invasive brain stimulation technique called transcranial temporal interference stimulation to see if it can improve memory and thinking skills in older adults with mild cognitive impairment (early memory loss that isn't yet dementia). Participants will receive the stimulation treatment and have their cognitive function monitored over time.
Shanghai, Shanghai MunicipalityAges 60–80 - NCT07474038Enrolling by invitation
AI-Supported Memory Training for Older Adults
This study tests a computer-based program that uses artificial intelligence (AI) to help older adults with mild memory problems improve their thinking skills. It is done remotely, so you can participate from home.
Pasadena, CaliforniaAges 65 years+ - NCT07449117Recruiting
Brain stimulation for language in mild cognitive decline
This study tests a new type of gentle brain stimulation (called temporal interference) to see if it can improve language processing in people with mild cognitive impairment. The stimulation uses electrodes placed on the head and is done while you are in an MRI scanner.
Brno, South MoravianAges 60–80 - NCT07441915Recruiting
Sleep Sounds and Brain Training for Parkinson's with Mild Memory Problems
This trial tests whether playing soft sounds during sleep can boost the effects of a computer-based brain training program in people with Parkinson's disease who have mild memory or thinking issues. If you qualify, you'll use a headband that plays tones while you sleep and do brain exercises for several weeks.
Zurich, Canton of ZurichAges 18 years+
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Cognitive Impairment trials by city
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Cognitive Impairment trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 569 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.