Clinical trials
Colorectal Surgery clinical trials
Below are recruiting colorectal surgery clinical trials, each written for real people, not researchers. We’re tracking 119 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06957236Enrolling by invitation
NICE Procedure for Benign Colon Disease
This trial tests a new minimally invasive surgery called the NICE procedure for treating benign left-sided colon diseases like diverticulitis or benign polyps. It aims to see if this approach leads to fewer infections and better recovery compared to standard surgery.
Houston, TexasAges 18 years+ - NCT06626399Recruiting
ChatGPT-4 for detecting surgical site infections after colorectal surgery
This trial tests whether ChatGPT-4 can help detect surgical site infections after colorectal surgery by looking at your electronic health records. It aims to improve infection monitoring without extra tests or visits.
Granollers, BarcelonaAges 18 years+ - NCT05941806RecruitingPhase 3
Preventing urinary retention after rectal surgery
This trial tests a medication called tamsulosin, given before and after rectal surgery, to see if it helps men urinate normally after the operation. It may help avoid the need for a temporary urinary catheter.
Québec, QuebecAges 18 years+ - NCT05334485RecruitingPhase 2/Phase 3
Pyridostigmine to treat slow bowel recovery after colorectal surgery
This trial tests whether pyridostigmine helps return bowel function faster after colorectal surgery when the gut is “stuck,” causing bloating and no gas or stool. It also checks safety and side effects compared with standard care.
Cleveland, OhioAges 18 years+ - NCT05133024RecruitingPhase 2
Beetroot juice to help prevent bowel slowdown after colon surgery
This Phase 2 study tests whether drinking beetroot juice can reduce “postoperative ileus,” when the intestines temporarily don’t move normally after colorectal surgery. If it works, it may help you recover bowel function sooner after an elective laparoscopic colon and upper rectum operation.
EdegemAges 18 years+ - NCT04359069Recruiting
Shorter urinary catheter time after pelvic surgery
This study looks at whether the urinary (Foley) catheter can stay in place for a shorter time after certain pelvic operations. It aims to see if timing of catheter removal is safer and more comfortable, especially for bladder function.
Los Angeles, CaliforniaAges 18 years+ - NCT05797077RecruitingPhase 3
After-surgery blood test–guided therapy for colon cancer liver spread
This Phase 3 trial tests whether an added “maintenance” treatment after liver surgery can help prevent colorectal cancer from coming back. It is only for people whose blood test (ctDNA) still shows signs of cancer after their operation.
Guangzhou, GuangdongAges 18–75 - NCT05566249Recruiting
Safety study of ArtiSential during rectal cancer surgery
This trial checks whether a tool called ArtiSential can be used safely and practically during planned rectal cancer operations. It may help the surgical team prepare and perform the operation more smoothly, but the main goal is safety and feasibility.
SeoulAges 18–80 - NCT07803601Recruiting
Magnesium through the vein to reduce inflammation after colon cancer surgery
This study tests whether giving magnesium through an IV during colon cancer surgery can lower the body's inflammation afterward, which may help you recover more smoothly. It is for people having open surgery for colon cancer.
Cairo, AbbassiaAges 35–75 - NCT07431892Recruiting
Pain after robotic vs. laparoscopic colon cancer surgery
This study compares pain levels after two types of minimally invasive colon cancer surgery: robotic and laparoscopic. It aims to see if one approach leads to less pain, which may help you recover more comfortably.
MadridAges 18 years+ - NCT07268846Recruiting
Prebiotic supplement before colorectal cancer surgery
This trial tests if taking a postbiotic supplement before surgery for colorectal cancer can improve recovery. It may help patients with adenocarcinoma of the large intestine prepare for their operation.
São Paulo, São PauloAges 18 years+ - NCT05148494RecruitingPhase 4
Enema versus drink for bowel prep before rectal surgery
This trial compares two bowel-clearing methods—an enema given through the rectum versus an oral (by mouth) mechanical bowel prep—during a specific type of rectal surgery. It aims to find which method works better and is easier or safer for patients.
Halifax, Nova ScotiaAges 18–75 - NCT01762813Recruiting
Study of blood/tissue markers in colorectal cancer surgery patients
This study looks at colorectal cancer patients who are planning curative surgery and collects related outcomes and lab “biomarker” information to better understand the disease. Your participation may help researchers connect test results to treatment results over time.
StavangerAges 18 years+ - NCT07588386Recruiting
Early Colonoscopy After Low Rectal Cancer Surgery
This study tests whether doing a colonoscopy (camera exam of the colon) early after surgery for low rectal cancer helps catch a serious complication called anastomotic leakage—when the surgical connection between bowel segments breaks down. Early detection might help prevent severe infections and improve outcomes.
Nanchong, SichuanAges 18–80 - NCT07068529Recruiting
Metabolic biomarkers for early diagnosis and recurrence of colorectal cancer
This study looks at metabolic biomarkers in blood and tumor tissue to help detect colorectal cancer earlier, predict outcomes, and monitor for recurrence. It includes both people newly diagnosed with colorectal cancer and healthy volunteers for comparison.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06350370Recruiting
Colorectal Cancer Outcomes with NOSES Surgery
This study tracks patients with colon or rectal cancer who have a special type of surgery called natural orifice specimen extraction surgery (NOSES). The goal is to see how well patients do short-term and long-term after this procedure.
Beijing, Beijing MunicipalityAges 18–75 - NCT02292641Recruiting
MRI study for repeat pelvic colorectal cancer
This study uses a special MRI to help understand and stage colorectal cancer that has come back in the pelvis. The goal is to improve how doctors make treatment decisions after previous surgery.
OsloAges 16 years+ - NCT02754115Recruiting
Audit of surgery with heated chemo for belly tumors
This study is an audit (a review of care) of patients who undergo cytoreductive surgery plus heated chemotherapy placed in the abdomen. It helps doctors understand how this treatment is done and what outcomes and safety it has.
Mumbai, MaharashtraAges 18–70 - NCT07432399RecruitingPhase 2
Lidocaine or dexamethasone before colon cancer surgery
This study tests whether giving lidocaine or a high-dose steroid before colon cancer surgery can improve immune function and recovery. The goal is to find a simple, safe way to help your body respond better during surgery.
LjubljanaAges 18 years+ - NCT05787197Recruiting
Blood test to guide treatment after colon cancer liver surgery
This trial studies a blood test (called ctDNA) in people with colon cancer that has spread to the liver and is being removed with curative surgery. The goal is to see how the blood test can help with planning and improving treatment after surgery.
BesançonAges 18 years+ - NCT06356558Recruiting
Making recovery programs easier for patients with limited health literacy
This study is testing ways to improve recovery programs for patients who may have trouble understanding health information. It aims to make these programs easier to follow, so patients can have better recovery after surgery.
Birmingham, AlabamaAges 18 years+ - NCT01416714Recruiting
Tissue sample collection during cancer surgery or biopsy
This study is collecting tissue samples from people with certain cancers while they have surgery or a biopsy. It may help researchers learn more about these cancers and improve future diagnosis and treatment.
Chicago, IllinoisAges Any age - NCT03837782Enrolling by invitation
Surgery outcomes for early to mid-stage colon cancer
This study looks at how well surgery works for people with colorectal cancer that has not spread to distant organs. It mainly includes patients who can have the tumor completely removed and accurately staged using lymph node samples.
Tianjin, Tianjin MunicipalityAges 18–90 - NCT05501353Recruiting
Study tumor biomarkers in recurrent metastatic colon cancer
This study looks for blood/tumor signals (“biomarkers”) that may help predict outcomes in people whose colorectal cancer returns and spreads after surgery. It mainly helps researchers understand who may do better or worse, which can guide future care.
Hangzhou, ZhejiangAges 18–99
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Common questions
- Are there clinical trials for colorectal surgery?
- Yes. Clin2 currently lists 119 recruiting colorectal surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.