Clinical trials · Boston, MA
Crohn’s disease clinical trials in Boston
We’re tracking 39 recruiting crohn’s disease studies with a site in or near Boston — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT05332639Recruiting
Risk tracking test for Crohn’s disease in teens
This study checks whether a personalized tool can estimate someone’s risk for Crohn’s disease before symptoms start. It may help families learn early risk and decide on next steps sooner.
Boston, MassachusettsAges 14 years+ - NCT05781152RecruitingPhase 4
Testing how new Crohn’s imaging and scopes predict outcomes
This study follows children newly diagnosed with Crohn’s disease to see how results from scans and endoscopy (camera scope) relate to outcomes over the first year. It may help doctors choose better early treatment plans and monitor children more effectively.
Boston, MassachusettsAges 6–17 - NCT05923073RecruitingPhase 3
Guselkumab for children with active Crohn’s disease
This Phase 3 trial tests guselkumab to treat children with moderately to severely active Crohn’s disease and ongoing inflammation in the bowel. If you qualify, the study will check whether the medicine can improve symptoms and healing, especially in children who did not respond to other treatments.
Boston, MassachusettsAges 2–17 - NCT06332534RecruitingPhase 3
Upadacitinib in children with moderate to severe Crohn's disease
This study tests an oral pill called upadacitinib for children with moderate to severe Crohn's disease that hasn't responded well to other treatments. It aims to see if the medicine can reduce inflammation and improve symptoms safely.
Boston, MassachusettsAges 2–17 - NCT04508088Recruiting
Study of bones and bone marrow in new Crohn’s
This study looks at how Crohn’s disease affects bones and bone marrow soon after diagnosis. It may help researchers understand disease effects and improve future care, either by comparing you to healthy controls or by tracking changes over time.
Boston, MassachusettsAges 13–20 - NCT03256240Recruiting
Two surgical options for Crohn’s bowel resection
This trial compares two ways of reconnecting the bowel after surgery in people with Crohn’s disease that affects the small intestine and/or colon. It aims to see which reconnection method works better after the initial surgery, even if you’re on Crohn’s medicines before the operation.
Boston, MassachusettsAges 18–90 - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Boston, MassachusettsAges 18 years+ - NCT04331639Recruiting
High-dose vitamin D for kids with IBD on biologic therapy
This trial studies whether giving a higher dose of vitamin D3 helps children and teens with inflammatory bowel disease (Crohn’s or ulcerative colitis) who have low vitamin D levels. Participants are already on biologic medicines and will be treated while monitoring blood (and safety) related to vitamin D.
Boston, MassachusettsAges 5–25 - NCT04779320RecruitingPhase 3
Vedolizumab for teens with moderate to severe Crohn's
This trial tests vedolizumab to treat children and teens with moderate to severe Crohn’s disease when standard treatments haven’t worked or caused side effects. It may help reduce gut inflammation and symptoms and help some patients stay healthier over time.
Boston, MassachusettsAges 2–17 - NCT04844606RecruitingPhase 3
Mirikizumab for kids with ulcerative colitis or Crohn’s
This study checks whether continuing mirikizumab (a medicine that calms gut inflammation) helps children with ulcerative colitis or Crohn’s disease after prior study treatment. It aims to see if staying on the medicine is beneficial and safe over time.
Boston, MassachusettsAges 2–19 - NCT05509777RecruitingPhase 3
Mirikizumab for children with active Crohn’s disease
This study tests mirikizumab to reduce inflammation and symptoms in children with Crohn’s disease that is currently active. It may help if your Crohn’s has not improved enough (or stopped working) with at least one other Crohn’s medicine.
Boston, MassachusettsAges 2–17 - NCT06655415Recruiting
Study for family members at risk of inflammatory bowel disease
This study follows people who have a parent, sibling, or child with Crohn's disease or ulcerative colitis to help understand why some family members develop the condition. If you are 14 or older and do not already have IBD, you may be able to join.
Boston, MassachusettsAges 14 years+ - NCT07219537Recruiting
Imaging the lower gut with a new capsule
This trial tests a new type of camera capsule that takes pictures of the lower part of your digestive tract. It may be an option for people who are healthy or have Lynch Syndrome and have had a recent normal colonoscopy.
Boston, MassachusettsAges 18–75 - NCT07237516Recruiting
Study of Zymfentra for people with Crohn's or colitis
This study follows adults with inflammatory bowel disease who are starting or switching to Zymfentra. Researchers will track your health over the next year to see how the medicine works in real life.
Boston, MassachusettsAges 18 years+ - NCT06424769Enrolling by invitation
Managing Inflammatory Bowel Disease with Text Message Surveys
This study aims to improve care and reduce health gaps for people with inflammatory bowel disease using text-message surveys to track symptoms and guide better disease management.
Boston, MassachusettsAges 13 years+ - NCT04263831RecruitingPhase 1/Phase 2
Low-dose IL-2 to treat Crohn’s disease flare-ups
This trial tests a low dose of IL-2 to reduce inflammation and help control Crohn’s disease symptoms. It’s for people whose Crohn’s disease hasn’t responded to at least one standard treatment or who need steroids to stay under control.
Boston, MassachusettsAges 12–80 - NCT05442567RecruitingPhase 3
Vedolizumab study for kids with ulcerative colitis or Crohn’s
This Phase 3 study tests whether vedolizumab can help children with ulcerative colitis (UC) or Crohn’s disease (CD) who improved on earlier treatment. It focuses on kids who can stay off steroid medicines and follow study visits and safety rules.
Boston, MassachusettsAges 2 years+ - NCT07033208Recruiting
Testing a wireless thermal capsule for the digestive tract
This study tests a new wireless capsule that you swallow, like a pill, to measure temperature inside your digestive tract. It is for healthy volunteers to see if the device is safe and works well.
Boston, MassachusettsAges 18–75 - NCT06430801RecruitingPhase 3
Study of tulisokibart for moderate to severe Crohn's disease
This trial tests a new medicine called tulisokibart for people with moderate to severe Crohn's disease. The medicine may help reduce inflammation and improve symptoms. It is for those who have not had success with other treatments.
Boston, MassachusettsAges 16–80 - NCT06958536RecruitingPhase 2
Testing a new drug for moderate to severe Crohn's disease
This study tests an experimental drug called SAR442970 for people with moderate to severe Crohn's disease who haven't had success with standard treatments or biologics. The goal is to see if it can reduce inflammation and improve symptoms.
Boston, MassachusettsAges 18–75 - NCT07352995Enrolling by invitation
Gut temperature study during colonoscopy
This study uses a special probe to measure temperature inside the colon during a routine colonoscopy. It may help researchers understand conditions like IBD, Crohn's disease, and ulcerative colitis.
Boston, MassachusettsAges 18 years+ - NCT07168499Recruiting
Diet, stress, and advanced therapy for Crohn's and colitis
This study tests whether adding a diet and stress management program to standard advanced therapy helps people with active Crohn's disease or ulcerative colitis feel better. It combines lifestyle changes with new medications to improve treatment outcomes.
Boston, MassachusettsAges 18 years+ - NCT05995353RecruitingPhase 3
Risankizumab for children with moderate to severe Crohn's
This study tests a new medicine called risankizumab for children with moderate to severe Crohn's disease. It is given as an IV infusion or a shot under the skin to see if it can reduce inflammation and improve symptoms.
Boston, MassachusettsAges 2–17 - NCT06819878RecruitingPhase 3
Afimkibart for moderate to severe Crohn's disease
This study tests an experimental drug called afimkibart for people with moderate to severe Crohn's disease who haven't responded well to other treatments. The goal is to see if the drug can help control symptoms and reduce inflammation over time.
Boston, MassachusettsAges 16–80
Hear when a new Crohn’s disease trial opens near Boston, MA
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Crohn’s disease trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting crohn’s disease studies listed above.
- Massachusetts General Hospital · 11 studies
- Boston Children's Hospital · 10 studies
- Brigham and Women's Hospital · 3 studies
- Hasbro Children's Hospital · 2 studies
- University Gastroenterology · 2 studies
- Boston Medical Center
- Boston University
- Dana-Farber Cancer Institute
What taking part in a crohn’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting crohn’s disease studies in Massachusetts.
Common questions
- Are there crohn’s disease clinical trials near Boston?
- Yes. We're currently tracking 39 recruiting crohn’s disease studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a crohn’s disease study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a crohn’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New crohn’s disease studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.