Clinical trials
Depression and Quality of Life clinical trials
Below are recruiting depression and quality of life clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07795216Recruiting
Affordable physical therapy for people with serious injuries
This trial tests a low-cost, personalized physical therapy program for people with serious injuries from accidents or trauma. It aims to help recovery without putting extra financial strain on you.
Nijmegen, GelderlandAges 18 years+ - NCT07773779Recruiting
App and nutrition support for blood sugar control
This study tests a smartphone app combined with dietary guidance to help adults with type 1 or type 2 diabetes improve their blood sugar levels. Participants will use the app with their continuous glucose monitor to track meals and get personalized support, with the goal of better glycemic control and quality of life.
New York, New YorkAges 18–75 - NCT07652333Recruiting
Strength training for muscle and mind on obesity medication
This study tests whether strength training can help adults taking new obesity medications (like Wegovy or Ozempic) maintain muscle and improve mental health. You would start the medication after your first study visit.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06702904Recruiting
Neuroprosthesis for phantom limb pain relief
This study tests a new type of artificial limb (neuroprosthesis) that sends signals back to your brain to help reduce phantom limb pain and improve your daily life. You may be able to join if you have had an arm or leg amputation at least 6 months ago and have persistent pain.
MoscowAges 18–65 - NCT07618572Recruiting
Cosmetics and Self-Esteem in Black Women with Skin Darkening
This study tests whether special cosmetic products can help improve dark marks on the skin (post-inflammatory hyperpigmentation) and boost self-esteem and quality of life in Black women. You'll use the cosmetics regularly and answer questions about how you feel.
São Paulo, São PauloAges 18–55 - NCT07546539Recruiting
Light Therapy for Chronic Fatigue Syndrome
This study tests whether a special type of light therapy (called photobiomodulation) can reduce severe tiredness in people with chronic fatigue syndrome. The light is applied to the skin and may help boost energy levels and improve daily function.
Larkana, SindhAges 18–60 - NCT07510984Recruiting
Heterotopic gastric mucosa and quality of life study
This study looks at how a condition called heterotopic gastric mucosa (HGM), which is stomach tissue in the wrong place in the esophagus, affects symptoms and quality of life. If you are scheduled for an upper endoscopy and are at least 18, you may be able to join.
Bottrop, North Rhine-WestphaliaAges 18 years+ - NCT07488351Recruiting
Self-kindness and confidence in Parkinson's: symptoms, function, quality of life
This study looks at how self-compassion and self-belief affect symptoms, daily function, and quality of life in people with Parkinson's disease. It aims to help researchers understand how emotional well-being relates to physical health.
Istanbul, TurkeyAges 40–85 - NCT07454733Recruiting
Do videos of clinic meetings improve quality of life in ALS?
This study looks at whether watching videos of your clinic team meetings helps improve quality of life for people with ALS and their caregivers. You and your caregiver would both take part, and you'd need to be able to use the internet and email.
Scottsdale, ArizonaAges 18 years+ - NCT07259577Recruiting
Vagus nerve stimulation for stroke recovery
This trial tests whether stimulating the vagus nerve can improve arm movement, breathing, and quality of life in people who had a stroke more than 6 months ago. It involves a non-invasive device that gently stimulates a nerve in the neck during therapy sessions.
Istanbul, IstanbulAges 18–70 - NCT07253298Enrolling by invitation
Kegel exercises with biofeedback for bowel recovery after rectal cancer surgery
This trial studies whether doing Kegel exercises with biofeedback (a technique that helps you see how your muscles are working) can improve bowel function, reduce emotional distress, and boost quality of life after rectal cancer surgery.
TaipeiAges 18 years+ - NCT07214415RecruitingPhase 2
Hyperbaric oxygen therapy for veterans with brain injury or mental health issues
This trial tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can improve thinking, mood, and quality of life in veterans with mild traumatic brain injury, PTSD, anxiety, or depression. You must have already tried at least one evidence-based therapy like CBT or EMDR.
Boise, IdahoAges 18–75 - NCT07167056Recruiting
AI chatbot to improve quality of life in cancer patients
This trial tests whether an AI-powered chatbot can help people with cancer feel better emotionally and improve their quality of life. You can join if you are currently in cancer treatment, feeling distressed, and have a smartphone.
Weston, FloridaAges 18 years+ - NCT07141108Recruiting
Using a digital tool to track chronic pain and improve quality of life
This trial tests a digital tool that helps you track your pain and activity level. The goal is to see if using the tool can improve your quality of life. You would use a smartphone or tablet app and share updates with your primary care team.
Malmö, Skåne CountyAges 18 years+ - NCT07126028Enrolling by invitation
Quality of life in kids after MIS-C
This study looks at how children feel and live their daily lives after recovering from MIS-C (a severe inflammatory condition linked to COVID-19). It compares them to healthy children of the same age and gender to see if there are any lasting effects.
Rijeka, Primorje-Gorski Kotar CountyAges 1 month–18 years - NCT07008950Recruiting
Health education for Syrian refugee young women in Lebanon
This study tests a program to help Syrian refugee women and girls learn about their bodies, relationships, and how to stay healthy. It aims to give them confidence and knowledge to make informed choices.
BeirutAges 15–15 - NCT06987175Recruiting
Sedante Neo therapy for low back pain
This study tests a therapy called Sedante Neo to see if it reduces pain, improves movement, and boosts quality of life in people with common low back pain. It is designed for adults aged 20–40 whose back pain is mild to moderate and affects daily life.
Lahore, Punjab ProvinceAges 5 months–9 months - NCT06939712Recruiting
Online mental health program for Crohn's patients
This study tests an online program that uses positive psychology to help improve mental health and quality of life in people with Crohn's disease who have mild anxiety or depression. The program is done over the internet, so you can join from home.
Hangzhou, ZhejiangAges 18–75 - NCT06938555Recruiting
Can extending nightly fasting improve sleep and thinking in breast cancer survivors?
This study tests whether eating all your meals within a shorter window each day (prolonged nightly fasting) can help improve sleep and thinking skills in breast cancer survivors who have memory or concentration problems.
Phoenix, ArizonaAges 18 years+ - NCT06802120Recruiting
Osteopathic care after lower back surgery
This trial tests whether osteopathic treatments can help reduce pain and improve daily life after spinal fusion surgery. It is for people who still have ongoing mechanical back pain four weeks after surgery.
ParisAges 18–75 - NCT04633655Recruiting
Study tests nerve side effects from certain chemotherapy drugs
This study looks at how chemotherapy that can affect nerves (“neurotoxic” chemo) changes nerve function over time. It may help researchers better measure nerve side effects and improve care for people who need these cancer treatments.
Birmingham, AlabamaAges 18 years+ - NCT06197165Recruiting
Shiatsu for amyloidosis symptoms and quality of life
This study tests whether shiatsu (a gentle Japanese touch therapy) can improve symptoms and quality of life for people with amyloidosis. If you have a bothersome symptom like pain, shortness of breath, or anxiety, this trial may help you feel better.
CréteilAges 18 years+ - NCT06129903Recruiting
Early psychiatric help for people with sarcoma
This study tests if getting a psychiatric consultation soon after a sarcoma diagnosis can improve mental health and quality of life. If you have a new sarcoma and need surgery at MSK, you may be able to join.
Basking Ridge, New JerseyAges 18 years+ - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+
Hear when a new Depression and Quality of Life trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for depression and quality of life?
- Yes. Clin2 currently lists 97 recruiting depression and quality of life studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression and quality of life trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression and quality of life trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.