Clinical trials · Pennsylvania
Depressive Symptoms clinical trials in Pennsylvania
We’re tracking 8 recruiting depressive symptoms studies with a site in Pennsylvania — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT05658796Recruiting
Program to reduce opioid use after hip or knee replacement
This trial tests a support program called RXWell to help people use less opioid pain medicine after elective hip or knee replacement surgery. It may help by addressing anxiety and depression symptoms that can affect pain and recovery.
Monroeville, PennsylvaniaAges 18–100 - NCT07055906Recruiting
Video coaching to help Latino families talk about race
This study tests a video-based coaching program to help Latino parents and their 10–14-year-old children talk about race and ethnic background. Families will be recorded having a conversation, then get feedback to strengthen their communication.
Harrisburg, PennsylvaniaAges 10–14 - NCT06559306RecruitingPhase 3
Seltorexant for depression with insomnia symptoms
This trial tests if adding seltorexant to your current antidepressant can improve depression and sleep problems. It is for people with major depressive disorder who still have symptoms, especially insomnia, despite trying at least one antidepressant.
Philadelphia, PennsylvaniaAges 18–74 - NCT06547489RecruitingPhase 2
Testing zelquistinel for major depression
This study tests whether zelquistinel, an investigational drug, can reduce symptoms of major depressive disorder (a type of clinical depression). It is for people who are currently experiencing a moderate to severe depressive episode and are not taking other antidepressants.
Allentown, PennsylvaniaAges 18–64 - NCT07115329RecruitingPhase 2
Testing Zelquistinel for major depression
This study tests a new oral medication called Zelquistinel (taken as a tablet) against a placebo for treating major depressive disorder. Researchers want to see if it can reduce depression symptoms, especially when other antidepressants haven't been tried or haven't worked.
Allentown, PennsylvaniaAges 18–64 - NCT05219955Recruiting
Study of caregiver stress and sleep in older adults
This study looks at how caregiver stress affects sleep problems—especially trouble getting going in the morning. If you are a caregiver for someone with dementia and have specific morning sleep/energy difficulties, you may be able to join and help researchers better understand what helps.
Pittsburgh, PennsylvaniaAges 55 years+ - NCT07020572Recruiting
Teen mood support program (iMATTER) in primary care
This study tests a group program to help teenagers with mild to moderate depression symptoms feel better. It takes place in primary care and uses a phone, computer, or tablet for activities.
Philadelphia, PennsylvaniaAges 13–17 - NCT05802004Recruiting
Sound stimulation to improve sleep and emotions in young adults
This study tests whether gentle sound stimulation during sleep can improve sleep and how you think and feel in daily life when you have anxiety or depression symptoms. You’ll also do sleep testing in a lab and complete questionnaires to measure changes.
Pittsburgh, PennsylvaniaAges 18–25
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting depressive symptoms studies listed above.
- Lehigh Center for Clinical Research · 2 studies
- Adams Clinical
- Children's Hospital of Philadelphia
- Parents and Children Together (PACT) Lab Space
- Scranton Medical Institute, LLC
- University of Pennsylvania
- University of Pittsburgh
- UPMC East
What taking part in a depressive symptoms study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Depressive Symptoms trials in other states
Common questions
- Are there depressive symptoms clinical trials in Pennsylvania?
- Yes. We're currently tracking 8 recruiting depressive symptoms studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a depressive symptoms study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a depressive symptoms trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New depressive symptoms studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.