Clinical trials
Digestive System Cancer clinical trials
Below are recruiting digestive system cancer clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06479070Recruiting
Using ctDNA to guide radiotherapy for head and neck cancer
This study looks at whether measuring a DNA fragment in the blood (called ctDNA) can help predict how well radiotherapy works for head and neck cancer. It may help doctors better tailor treatment for patients with stage III or IV disease.
Caen, CaenAges 18 years+ - NCT07620951RecruitingPhase 1
How Your Body Processes an Experimental Cancer Drug
This is an early-stage study testing how a new cancer medication (zorifertinib) moves through and leaves a healthy male body. Researchers use a special radioactive marker to track the drug so they can understand how it works and how safe it is.
Suzhou, JiangsuAges 18–45 - NCT05956847Recruiting
Studying DNA fragments in stomach cancer tissue
This trial looks at tiny pieces of DNA found outside cells in stomach tissue to better understand how gastric (stomach) cancer starts and progresses. It may help future patients by improving how doctors study stomach cancer from biopsy and surgical samples.
Xi'an, ShaanxiAges 18–80 - NCT06353854Recruiting
Study of biomarkers in MSI-high colorectal cancer patients on immunotherapy
This trial is studying people with a specific type of advanced colorectal cancer (MSI-high/dMMR) who are starting immunotherapy with pembrolizumab. The goal is to find out which markers in the tumor might predict whether the treatment works well.
BayonneAges 18 years+ - NCT07283653Recruiting
Using DIGEST™ to measure swallowing problems in cancer patients
This trial is testing how well a tool called DIGEST™ works to measure swallowing difficulties (dysphagia) in cancer patients who have a special x-ray called a Modified Barium Swallow. The goal is to help doctors better understand and treat swallowing problems.
Houston, TexasAges 18 years+ - NCT06902467Recruiting
Chemotherapy directly into the abdomen after surgery for advanced ovarian cancer
This trial tests giving chemotherapy directly into the abdomen (intraperitoneal) after optimal surgery for advanced ovarian cancer. It aims to see if this approach is safe and effective for women who have already received 3-4 cycles of chemotherapy before surgery.
MurciaAges 18–70 - NCT06655259RecruitingPhase 2
TURP with standard therapy for metastatic prostate cancer
This trial tests whether adding a surgery called TURP (transurethral resection of the prostate) to the usual hormone therapy and chemotherapy can help men with metastatic prostate cancer that has spread to lymph nodes, bone, or other organs. The surgery helps relieve urinary symptoms and may improve how well the cancer responds to treatment.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05431738Recruiting
Anti-migration stent for swallowing blockage from reflux cancer
This trial studies a special anti-migration stent placed in the esophagus to help keep a tumor-related blockage open and reduce reflux-related problems. It’s for adults whose swallowing is difficult because of a cancer narrowing at the esophagus-stomach junction.
ParisAges 18–91 - NCT06207656RecruitingPhase 2
Targeted therapy for BRAF V600E mutated colorectal cancer
This trial tests if combining three targeted drugs (cetuximab, encorafenib, and binimetinib) before surgery can shrink or control cancer in people with a specific BRAF V600E mutation and a stable (MSS) tumor. It focuses on colorectal cancer that is either already able to be removed or could become removable with treatment.
MadridAges 18 years+ - NCT05706779RecruitingPhase 2
Encorafenib plus cetuximab before surgery for BRAF-mutated colon cancer
This trial tests whether giving encorafenib and cetuximab before surgery can shrink or control BRAF-mutated colon or upper rectal cancer and make surgery more effective. It also checks whether this approach is safe and helps patients do better overall.
ParisAges 18 years+ - NCT07124858Recruiting
Fruquintinib for advanced colorectal cancer
This study tracks how well fruquintinib works for people with advanced colorectal cancer that has spread. It aims to find factors that predict better outcomes, using blood and tumor samples.
Poitiers, FranceAges 18 years+ - NCT06929949Recruiting
Best Reconnection Method After Upper Stomach Surgery
This study compares different ways of reconnecting the digestive tract after surgery to remove the upper part of the stomach. It aims to see which method leads to a better quality of life for people with early-stage stomach or esophageal junction cancer.
Changchun, JilinAges 18–75 - NCT06207981RecruitingPhase 3
Comparing two treatment plans for advanced anal cancer
This trial tests if giving chemotherapy before standard chemoradiation works better than standard chemoradiation alone for people with locally advanced anal cancer that has not spread. It aims to improve treatment outcomes.
AgenAges 18 years+ - NCT02885753RecruitingPhase 3
Liver-only metastatic colon cancer trial using targeted chemo
This Phase 3 trial tests different ways to deliver chemotherapy for colon cancer that has spread only to the liver (with limited possible tiny lung spots). It looks at whether the treatment plan improves outcomes compared with another chemotherapy approach, using oxaliplatin and LV5FU2 (with or without irinotecan) plus an added targeted medicine.
BrusselsAges 18 years+
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Common questions
- Are there clinical trials for digestive system cancer?
- Yes. Clin2 currently lists 62 recruiting digestive system cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a digestive system cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a digestive system cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.